Problems in the Therapy of Aids‐associated Malignancies

Wittes, Robert E.; Killen, John Y.

doi:10.1111/j.1749-6632.1984.tb37167.x

Cited by 4 publications

(4 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The importance of obtaining a complete response is emphasized by the finding that mortality is twice as high in patients with a n incomplete response as in those with a complete response (Ziegler et al, 1984). As would be expected, this aggressive approach to treatment is frequently associated with infection, and relapses are common Wittes and Killen, 1984;Ziegler et al, 1984).…”

Section: Treatment Of Hw-associated Malignanciesmentioning

confidence: 88%

Section: Treatment Of Hw-associated Malignanciesmentioning

confidence: 99%

“…Treatment of HIV-associated lymphoma Lymphomas in patients with H N infection tend to be rapidly progressive and generally pose a major threat to life Wittes and Killen, 1984). Therefore, aggressive treatment is usually indicated with a goal of achieving a rapid and complete remis-sion Wittes and Killen, 1984). Standard combination chemotherapeutic regimens appropriate for the histologic type of lymphoma are utilized, and radiation is used in conjuction with systemic chemotherapy in some cases (Abrams et al, 1986;Gill et al, 1985;Longo et al, 1984;Wittes and Killen, 1984;Ziegler et al, 1984).…”

Section: Treatment Of Hw-associated Malignanciesmentioning

confidence: 99%

“…Therefore, aggressive treatment is usually indicated with a goal of achieving a rapid and complete remis-sion Wittes and Killen, 1984). Standard combination chemotherapeutic regimens appropriate for the histologic type of lymphoma are utilized, and radiation is used in conjuction with systemic chemotherapy in some cases (Abrams et al, 1986;Gill et al, 1985;Longo et al, 1984;Wittes and Killen, 1984;Ziegler et al, 1984). A complete remission is achieved in about 50% of patients (Abrams et al, 1986;Ziegler et al, 19841, compared to complete remission rates of 70 to 90% for comparable histologic types of lymphoma in patients without HIV infection (Ziegler et al, 1984).…”

Section: Treatment Of Hw-associated Malignanciesmentioning

confidence: 99%

See 3 more Smart Citations

Malignancies in the acquired immunodeficiency syndrome

1988

J. Elec. Microsc. Tech.

View full text Add to dashboard Cite

Malignancies frequently arise in patients infected with human immunodeficiency virus (HIV), including those patients classified as having the acquired immunodeficiency syndrome (AIDS). Currently, Kaposi's sarcoma and certain types of lymphoma are considered to develop as a result of HIV infection, and other cancers have also been reported in these patients. For the most part, ultrastructural study of HIV-associated malignancies has been limited to Kaposi's sarcoma; the ultrastructural features of the epidemic form of this disease are generally the same as those of the classical form. The occurrence of these cancers in HIV-infected individuals appears to be related to the immunodeficiency caused by this virus, but the basic etiologic mechanisms remain unknown. In general, only palliative treatments are presently available for HIV-associated malignancies.

show abstract

Section: Treatment Of Hw-associated Malignanciesmentioning

confidence: 88%

Section: Treatment Of Hw-associated Malignanciesmentioning

confidence: 99%

Section: Treatment Of Hw-associated Malignanciesmentioning

confidence: 99%

Section: Treatment Of Hw-associated Malignanciesmentioning

confidence: 99%

See 2 more Smart Citations

Malignancies in the acquired immunodeficiency syndrome

1988

J. Elec. Microsc. Tech.

View full text Add to dashboard Cite

show abstract

Colonic adenocarcinoma associated with the acquired immune deficiency syndrome

Cappell

Yao

Cho

1988

Cancer

View full text Add to dashboard Cite

Colonic adenocarcinoma developed in an intravenous drug abuser with the acquired immune deficiency syndrome (AIDS) that was diagnosed by the presence of antibodies to the human immunodeficiency virus (HIV), generalized lymphadenopathy, and biopsy proven esophageal candidiasis. The colon cancer presented atypically at a young age with no known risk factors and with a bulky primary tumor and a local fistula. AIDS and AIDS risk factors have been associated with Kaposi's sarcoma, lymphomas, and anal and oropharyngeal carcinoma. This report suggests a possible association between colonic adenocarcinoma and AIDS.

show abstract

Viral infections in the acquired immunodeficiency syndrome

Miller

Howell

1988

J. Elec. Microsc. Tech.

View full text Add to dashboard Cite

The following communication is a tripartite synopsis of the role of viral infection in the acquired immunodeficiency syndrome (AIDS). The first section describes the impact of viral opportunistic infection in AIDS; for each virus, clinical presentation and diagnosis, laboratory diagnostic approaches (with emphasis on electron microscopy), and therapeutic interventions attempted to date are discussed. The second segment explores current theories on the pathogenesis of AIDS, and describes diagnostic and therapeutic approaches to the syndrome itself. The final section catalogues ultrastructural anomalies in the cells of AIDS patients, many of which have been mistakenly identified as etiologic agents.

show abstract

Problems in the Therapy of Aids‐associated Malignancies

Cited by 4 publications

References 28 publications

Malignancies in the acquired immunodeficiency syndrome

Malignancies in the acquired immunodeficiency syndrome

Colonic adenocarcinoma associated with the acquired immune deficiency syndrome

Viral infections in the acquired immunodeficiency syndrome

Contact Info

Product

Resources

About