Procalcitonin and proinflammatory parameters in diabetic foot infection as new predictive factor

Raheem, Shler Gh.; AL-Barzinji, Ruqaya M.; Mansoor, Husham Y.; Al-Dabbagh, Ali

doi:10.1063/1.5004320

Cited by 2 publications

(2 citation statements)

References 35 publications

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“…The result showed there was significance difference among the patients, they observed that male more frequency than female 78% vs 22%, as shown in Table (2). While Kadhim, 2021; QADIR et al, 2020 [2], [12] contrasted with present results showed there was no significance different between male and female in studied groups. Male predominance in DFU could be linked to factors such as sex-related differences in life styles and professional roles that require the feet to tolerate more pressure.…”

Section: Discussioncontrasting

confidence: 44%

Role of interleukin-6 in diabetic foot ulcers patients in Thi-Qar Provence

Katya

Salman

Mohammed

2022

ijhs

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The aim of this study is to evaluate the level of Interleukin-6 in patient with diabetic foot ulcers. The present study was carried out in the Diabetes and Endocrinology Center of the Health Directorate at Thi-Qar Provence, at the period between January to July (2022). The immune status investigates for patients with diabetic foot ulcers by measuring the levels of Interleukin-6 (IL-6) in serum using a technique enzyme-linked immune Sorbent adsorptive (ELISA). The study included 100 subjects, (50) patients with diabetic foot and (50) were healthy control. The statistical analysis showed that a high significant increase (P≤0.01) in serum the rate of concentration of (IL-6) in patients (6.16 ± 5.24) pg/ml compared to the healthy control group (5.42 ± 7.74) pg/ml with significant difference (0.01). These results revealed that the excessive presence of (IL-6) might play a role in Thi-Qar Provence population.

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Section: Discussioncontrasting

confidence: 44%

Role of interleukin-6 in diabetic foot ulcers patients in Thi-Qar Provence

Katya

Salman

Mohammed

2022

ijhs

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“…Raheem et al divided diabetic foot patients into subgroups according to the Wagner classification and examined their CRP levels. They reported that there was no statistically significant difference between grades 1 and 2, and the highest CRP levels were detected in grade 5 30 . Hadavand et al compared only the CRP levels of grades 3 and 4 and found that the CRP levels of grade 4 were statistically significantly higher than those in grade 3 22 .…”

Section: Discussionmentioning

confidence: 98%

Is ischaemia‐modified albumin a biomarker in wagner classification in diabetic foot ulcers?

Özkan

Adanaş

Hakan

2021

Int J Clinical Practice

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Diabetes mellitus, one of the most common chronic metabolic diseases worldwide, is characterised by high blood sugar and leads to many serious complications. 1 The complications caused by longterm high blood glucose include nephropathy, retinopathy and neurovascular complications. 2 One of the most serious conditions of diabetes-related neurovascular complications is foot ulcers. It was estimated that ~15% of people with type 2 diabetes would be affected by foot ulcers. 3 However, in 2015, the International Diabetes Federation reported that this rate was ~34%. 4 Diabetic foot ulcers lead to amputation at various levels, depending on severity, in ~20% of patients. Furthermore, diabetic foot ulcers increase the risk of death. Patients with diabetic foot ulcers have a 2.5-fold higher risk of death at 5 years than those without diabetic foot ulcers. 5 Unfortunately, despite significant improvements in diabetic foot care and treatment, the rate of amputation due to diabetic foot ulcers is increasing.One of the classifications of diabetic foot ulcers was developed by Wagner in the 1970s, in which ulcers were graded between 0 and 5. In this classification, only the depth of the ulcer, osteomyelitis and gangrene are evaluated, but the presence of ischaemia is not considered. 6,7 New classification systems have been developed after this classification; however, the Wagner classification is simple and very effective in predicting low extremity amputation. 8,9 Ischaemia in tissues due to the decreased blood flow in diabetic foot ulcers is not considered in the Wagner classification, making it difficult to determine the level of amputation. Therefore, a biomarker to help determine the level of ischaemia in these patients may be more effective in determining the degree of amputation. Classical

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Procalcitonin and proinflammatory parameters in diabetic foot infection as new predictive factor

Cited by 2 publications

References 35 publications

Role of interleukin-6 in diabetic foot ulcers patients in Thi-Qar Provence

Role of interleukin-6 in diabetic foot ulcers patients in Thi-Qar Provence

Is ischaemia‐modified albumin a biomarker in wagner classification in diabetic foot ulcers?

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