Process engineering for a membrane recycle fermentor

Groot, Wim; Lans, R. G. J. M. van der; Luyben, K. Ch. A. M.

doi:10.1007/bf00369835

Cited by 4 publications

(1 citation statement)

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“…Owing to the low microalgal cell concentration and metabolite productivity under natural conditions, these systems are promising. Bioreactors coupled with tangential micro-or ultra®ltration are widely used for fermentation processes with different con®gurations [12], and have been developed, more recently, for the production of a variety of compounds by different micro-organisms including microalgae. The major limitations of this continuous system are membrane fouling [13], and hydrodynamic shear stress on cells [14].…”

Section: Introductionmentioning

confidence: 99%

Comparison of two membrane – photobioreactors, with free or immobilized cells, for the production of pigments by a marine diatom

Rossignol¹,

Lebeau

Jaouen³

et al. 2000

Bioprocess Engineering

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The present study concerns the value enhancement of the microalga Haslea ostrearia. This marine diatom bears the peculiarity of synthesizing and secreting in the culture medium a blue-green pigment named`m arennine''. Anticancer research, cosmetics and aquaculture are the ®elds concerned with the utilizations of this hydrosoluble pigment. The aim of the study is to compare the pigment productivity obtained with two types of photobioreactors. In the ®rst process, cells are free and recycled in a bioreactor combined with a membrane ultra®ltration equipment (external loop). In the second system, cells are entrapped in a tubular agar gel layer in a photobioreactor of original design. The in¯uence of nitrate concentration and renewal rate is examined. Experiments, conducted on long term periods (up to 40 d) without any external contamination, revealed that marennine productivities of more than 5±7 mg 10 9 cell )1 d )1 can be reached with both bioreactors. The advantages and drawbacks of each process design are also discussed.

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Section: Introductionmentioning

confidence: 99%