Processing of 45S5 Bioglass® by lithography-based additive manufacturing

Tesavibul, Passakorn; Felzmann, Ruth; Gruber, Simon; Liska, Robert; Thompson, Ian D.; Boccaccını, Aldo R.; Stampfl, Juergen

doi:10.1016/j.matlet.2012.01.019

Cited by 169 publications

(89 citation statements)

References 18 publications

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“…Also, Gmeiner et al [104] successfully fabricated 3D dense bioactive glass-ceramic structures with increased mechanical properties and scaffolds with an accuracy of up to 25 Â 25 Â 25 μm 3 using ceramic and glassceramic slurries and the SLA technique. Tesavibul et al [105] obtained a highly bioactive glass scaffold using lithography-based additive manufacturing. The technique allowed the tailoring of the scaffold's macroscopic and microstructural features, developing scaffolds with a pore size of 500 μm.…”

Section: Stereolithography (Sla)mentioning

confidence: 99%

Bioactive Glass-Biopolymer Composites for Applications in Tissue Engineering

Ding¹,

Souza²,

Li³

et al. 2016

Handbook of Bioceramics and Biocomposites

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Section: Stereolithography (Sla)mentioning

confidence: 99%

Bioactive Glass-Biopolymer Composites for Applications in Tissue Engineering

Ding¹,

Souza²,

Li³

et al. 2016

Handbook of Bioceramics and Biocomposites

Self Cite

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“…Also, Gmeiner et al [103] successfully fabricated 3D dense bioactive glass-ceramic structures with increased mechanical properties and scaffolds with an accuracy of up to 25 Â 25 Â 25 mm 3 using ceramic and glass-ceramic slurries and the SLA technique. Tesavibul et al [104] obtained a highly bioactive glass scaffold using lithography-based additive manufacturing. The technique allowed the tailoring of the scaffold's macroscopic and microstructural features, developing scaffolds with a pore size of 500 mm.…”

Section: Stereolithography (Sla)mentioning

confidence: 99%

Bioactive Glass-Biopolymer Composites

Ding¹,

Souza²,

Li³

et al. 2015

Handbook of Bioceramics and Biocomposites

Self Cite

View full text Add to dashboard Cite

Tissue engineering (TE) is a biomedical field in continuous expansion. However, there are still many challenges, and the further development of TE approaches requires interdisciplinary interaction and collaboration among various research areas with a notable contribution expected from biomaterials science. In the last couple of decades, significant advances in the development of biomaterial-based scaffolds for hard and soft tissue regeneration have been accomplished, including the manufacture of biocomposites that combine natural or synthetic polymers with bioactive glasses or glass-ceramics. These novel biomaterials present the possibility of tailoring a variety of parameters and properties such as degradation kinetics, mechanical properties, and chemical composition according to the aimed application. This chapter presents a concise update of the field of biopolymer-bioactive glass composite scaffold development for TE covering several popular processing techniques for biocomposite fabrication, namely, microsphere processing, solvent casting-particulate leaching method, electrospinning, freezedrying, and rapid prototyping techniques, which lead to scaffolds exhibiting a variety of 3D morphologies and different pore structures.

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“…Following in vivo experiments even showed a higher amount of incorporated new bone in comparison to smooth implants [22]. Porous structures were realized by lithography-based additive manufacturing as well, creating crystallized bioglass samples [23]. Efforts have also been made to structure bioglass, showing alignment of osteoblast-like MG-63 cells.…”

Section: Introductionmentioning

confidence: 99%

Structuring of bioactive glass surfaces at the micrometer scale by direct casting intended to influence cell response

Pföss¹,

Bührig–Polaczek²,

Fischer³

et al. 2016

Biomedical Glasses

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Defect-free bioactive glass surfaces with a grooved microstructure at the low micrometer scale were achieved by a mold casting process. The process was applied to the well-known glass compositions 45S5 and 13-93. Such microstructured surfaces may exhibit especially favorable conditions for bone cell orientation and growth. The aim of the study was to assess the parameter range for a successful casting process and thus to produce samples suitable to investigate the interaction between structured surfaces and relevant cells. Viscous flow in its temperature dependence and thermal analysis were analyzed to identify a suitable process window and to design a manageable time-temperature process scheme. Counteracting effects such as formation of chill ripples, mold sticking and build-up of permanent thermal stress in the glass had to be overcome. A platinum gold alloy was chosen as mold material with the mold surface bearing the mother shape of the microstructure to be imprinted on the glass surface. First experiments studying the behavior of osteoblast-like cells, seeded on these microstructured glass surfaces revealed excellent viability and an orientation of the cells along the microgrooves. The presented results show that direct casting is a suitable process to produce defined microstructures on bioactive glass surfaces.

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Processing of 45S5 Bioglass® by lithography-based additive manufacturing

Cited by 169 publications

References 18 publications

Bioactive Glass-Biopolymer Composites for Applications in Tissue Engineering

Bioactive Glass-Biopolymer Composites for Applications in Tissue Engineering

Bioactive Glass-Biopolymer Composites

Structuring of bioactive glass surfaces at the micrometer scale by direct casting intended to influence cell response

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