Processing of Differentially Valued Rewards and Punishments in Youths with Bipolar Disorder or Severe Mood Dysregulation

Rau, Geoff; Blair, Karina S.; Berghorst, Lisa H.; Knopf, Lisa; Skup, Martha; Luckenbaugh, David A.; Pine, Daniel S.; Blair, R. J. R.; Leibenluft, Ellen

doi:10.1089/cap.2007.0053

Cited by 22 publications

(16 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Further, the boys with ODD exhibited lower skin conductance responses that were positively related to the speed with which they initiated the next trial. These findings contrast others that show no differences in reward or punishment processing between children with SMD and healthy controls (Rau et al, 2008). This suggests that characterizing RPE-related processes may provide a useful distinction between youth with SMD and those with ODD.…”

Section: Frustration Reward and Non-rewardcontrasting

confidence: 99%

“…However, the nature of these disruptions in DMDD is not easily determined from the extant literature as it appears to differ depending on the psychopathology studied. For example, children with irritability in the context of ODD exhibit reduced physiological responding to punishment (Luman et al, 2010; Matthys et al, 2004) that is not observed in studies of children with SMD (Rau et al, 2008). Similarly, children with disruptive behavior disorders including ODD do not show the typical decrease in striatal activity during non- reward (Gatzke-Kopp et al, 2009), while chronically, irritable youth (children with SMD), show an enhanced decrease in striatal activity in response to punishment (Deveney et al, 2013).…”

Section: Frustration Reward and Non-rewardmentioning

confidence: 91%

See 1 more Smart Citation

Disruptive Mood Dysregulation Disorder (DMDD): An RDoC perspective

Meyers

DeSerisy

Roy

2017

Journal of Affective Disorders

View full text Add to dashboard Cite

In recent years, there has been much debate regarding the most appropriate diagnostic classification of children exhibiting emotion dysregulation in the form of irritability and severe temper outbursts. Most recently, this has resulted in the addition of a new diagnosis, Disruptive Mood Dysregulation Disorder (DMDD) in the DSM 5. The impetus for including this new disorder was to reduce the number of diagnoses that these children would typically receive; however, there is concern that it has only complicated matters rather than simplifying them. For example, a recent epidemiologic study shows that DMDD cannot be differentiated from oppositional defiant disorder (ODD) based on symptoms alone. Thus, these children are an ideal population in which to apply RDoC constructs in order to obtain greater clarity in terms of underlying processes and ultimately, inform nosology and appropriate interventions. The aim of this article is to provide a foundation for future research by examining extant theoretical and empirical evidence for the role of four key RDoC constructs in DMDD.

show abstract

Section: Frustration Reward and Non-rewardcontrasting

confidence: 99%

Section: Frustration Reward and Non-rewardmentioning

confidence: 91%

Disruptive Mood Dysregulation Disorder (DMDD): An RDoC perspective

Meyers

DeSerisy

Roy

2017

Journal of Affective Disorders

View full text Add to dashboard Cite

show abstract

“…19 In addition, neuropsychological and imaging data gave further contributions to the differentiation between BD and chronic irritability. 20–22 …”

Section: The Controversy About Irritability and Youth Bipolar Diagnosismentioning

confidence: 99%

Irritability in children and adolescents: past concepts, current debates, and future opportunities

Krieger

Leibenluft²,

Stringaris

et al. 2013

Rev. Bras. Psiquiatr.

Self Cite

View full text Add to dashboard Cite

Irritability is defined as a low threshold to experience anger in response to frustration. It is one of the most common symptoms in youth and is part of the clinical presentation of several disorders. Irritability can present early in life and is a predictor of long-term psychopathology; yet, the diagnostic status of irritability is a matter of intense debate. In the present article, we address two main components of the debate regarding irritability in youth: the misdiagnosis of chronic irritability as pediatric bipolar disorder, and the proposal of a new diagnosis in the DSM-5, disruptive mood dysregulation disorder, whose defining symptoms are chronic irritability and temper outbursts.

show abstract

“…Existing findings on reward dysregulation and BPSD diagnosis and mood symptoms in adolescence are mixed. On the one hand, differential reward learning tasks demonstrate no group differences between adolescents with BPSD from controls (Rau et al, 2008). On the other hand, adolescents with BPSD do exhibit impairment in tasks assessing the ability to adapt to changing reward contingencies (Dickstein et al, 2007; Dickstein et al, 2004; Gorrindo et al, 2005).…”

mentioning

confidence: 96%

Reward Dysregulation and Mood Symptoms in an Adolescent Outpatient Sample

Gruber

Gilbert

Youngstrom

et al. 2013

J Abnorm Child Psychol

View full text Add to dashboard Cite

Research on bipolar spectrum disorders (BPSD) in adolescence has burgeoned in the last decade, but continued work is needed to identify endophenotypic markers associated with illness onset and course. The present study examined reward dysregulation – measured via the behavioral activation system (BAS) – as one putative marker of BPSD in adolescence. A diverse group of 425 outpatient adolescents between 11–17 years of age (52% male) completed the Behavioral Inhibition and Activation Scale (BIS-BAS) scale to measure reward dysregulation. Semi-structured interviews determined diagnoses and severity of mood symptoms. Parent-reported BAS was associated with increased symptoms of mania, and parent and adolescent-reported BAS were associated with symptoms of depression. Parent-reported BIS scores were associated with increased symptoms of mania. Results held independent of diagnostic status. Furthermore, parent BIS/BAS reports were stronger predictors for manic symptoms compared to adolescent-reports. Results extend work in adults with BPSD, suggesting a transdiagnostic association between reward dysregulation and mood symptom severity in adolescence.

show abstract

Processing of Differentially Valued Rewards and Punishments in Youths with Bipolar Disorder or Severe Mood Dysregulation

Cited by 22 publications

References 32 publications

Disruptive Mood Dysregulation Disorder (DMDD): An RDoC perspective

Disruptive Mood Dysregulation Disorder (DMDD): An RDoC perspective

Irritability in children and adolescents: past concepts, current debates, and future opportunities

Reward Dysregulation and Mood Symptoms in an Adolescent Outpatient Sample

Contact Info

Product

Resources

About