Procurement technique for isolated small bowel, pancreas, and liver from multiorgan cadaveric donor

Jovine, Elio; Benedetto, Fabrizio Di; Quintini, Cristiano; Masetti, Michele; Cautero, N.; Gelmini, Roberta; Andreotti, Alessia; Bezer, Lamia; Sassi, Sadok; Boggi, Ugo; Filipponi, Franco; Pinna, A.D.

doi:10.1016/s0041-1345(02)02661-1

Cited by 12 publications

(6 citation statements)

References 4 publications

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“…Celsior is an extracellular type of preservation solution developed by Menasché et al in 1994 for cold storage preservation of cardiac grafts 21 . Currently, it has been applied successfully to heart, lung, liver, pancreas, kidney, and small bowel preservation 44,45 . Celsior is a high-sodium, low-potassium solution.…”

Section: Commonly Used Solutions For Kidney Preservationmentioning

confidence: 99%

Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms

et al. 2019

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Solid organ transplantation was one of the greatest medical advances during the past few decades. Organ preservation solutions have been applied to diminish ischemic/hypoxic injury during cold storage and improve graft survival. In this article, we provide a general review of the history and advances of preservation solutions for kidney transplantation. Key components of commonly used solutions are listed, and effective supplementations for current available preservation solutions are discussed. At cellular and molecular levels, further insights were provided into the pathophysiological mechanisms of effective ingredients against ischemic/hypoxic renal injury during cold storage. We pay special attention to the cellular and molecular events during transplantation, including ATP depletion, acidosis, mitochondrial dysfunction, oxidative stress, inflammation, and other intracellular mechanisms.

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Section: Commonly Used Solutions For Kidney Preservationmentioning

confidence: 99%

Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms

et al. 2019

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“…Reduced glutathione is added as a free-radical scavenger. Currently, it has been successfully used in clinical heart, lung, liver, pancreas, kidney, and small bowel preservation (91,92). The likelihood whether Celsior will eventually replace UW-CSS may depend on the results of a sufficiently powered multicenter trial.…”

Section: Celsior Solutionmentioning

confidence: 99%

Perspectives in Organ Preservation

2007

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Maintaining organ viability after donation until transplantation is critically important for optimal graft function and survival. To date, static cold storage is the most widely used form of preservation in every day clinical practice. Although simple and effective, it is questionable whether this method is able to prevent deterioration of organ quality in the present era with increasing numbers of organs retrieved from older, more marginal, and even non-heart-beating donors. This review describes principles involved in effective preservation and focuses on some basic components and methods of abdominal organ preservation in clinical and experimental transplantation. Concepts and developments to reduce ischemia related injury are discussed, including hypothermic machine perfusion. Despite the fact that hypothermic machine perfusion might be superior to static cold storage preservation, organs are still exposed to hypothermia induced damage. Therefore, recently some groups have pointed at the beneficial effects of normothermic machine perfusion as a new perspective in organ preservation and transplantation.

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“…All donors were cytomegalovirus (CMV) negative. Details of the surgical technique for different types of ISB/MV allografts have been described elsewhere (12,13).…”

Section: Resultsmentioning

confidence: 99%

Intestinal Transplantation for Chronic Intestinal Pseudo-Obstruction in Adult Patients

Masetti

Benedetto

Cautero

et al. 2004

American Journal of Transplantation

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Procurement technique for isolated small bowel, pancreas, and liver from multiorgan cadaveric donor

Cited by 12 publications

References 4 publications

Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms

Preservation Solutions for Kidney Transplantation: History, Advances and Mechanisms

Perspectives in Organ Preservation

Intestinal Transplantation for Chronic Intestinal Pseudo-Obstruction in Adult Patients

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