This study investigates regiocentric SMEs and the impact of their products on Brebes Regency's regional revenue. The outcomes of this investigation were evaluated utilizing the AMOS 22 analytic software and Structural Equation Modeling (SEM). The theoretical implication of this study is that product configuration capabilities, entrepreneurial orientation, and market orientation influence regiocentric SME performance. In the meantime, regional revenue is influenced by the benefits of regiocentric small and medium-sized enterprises (SMEs), product configuration capabilities, entrepreneurial orientation, and market orientation. According to the findings of this investigation, hypothesis 1 demonstrates significant results with a value of CR = 2,996 1.96 and a probability of 0.003, meaning that H1 is acceptable. Testing hypothesis 2 shows significant results with a value of CR = 4.093 1.96 with probability = 0.000; the probability of qualifying the test below 0.05 means that H2 of this study is acceptable. If testing hypothesis 3 yields significant results with CR = 2,435.196 and probability = 0.015, then the probability of testing meeting the requirements is less than 0.05, making H3 acceptable. Testing hypothesis 4 yields significant results with a value of CR = 3.707 1.96 and a probability value of 0.000; hence, the test probability is less than 0.05, indicating that H4 is acceptable.