Production and Structure Elucidation of Glycoglycerolipids from a Marine Sponge-Associated <i>Microbacterium</i> Species

Wicke, Corinna; Hüners, M.; Wray, Victor; Nimtz, Manfred; Bilitewski, Ulrich; Lang, Siegmund

doi:10.1021/np990313b

Cited by 63 publications

(34 citation statements)

References 20 publications

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“…strain HP2, which was isolated from a Antimicrobial activities were determined as inhibition zones (in mm) measured from the edge of the disc after 24 h of incubation. The bacteria used in this experiment are: S. aur-Staphylococcus aureus, S. epi-Staphylococcus epidermidis, S. mar-Serratia marcescens, K. pneKlebsiella pneumonia, S. typ-Salmonella typhi, S. ent-Salmonella entertidis a Mediterranean sponge Halichondria panicea, was able to synthesize a new glucosyl-mannosyl-glycerolipid, an antitumor agent (Wicke et al 2000). The reason for the low activity of strains is possibly due to the fact that these pathogenic bacteria are not natural competitors for the epibiotic bacteria and therefore lack a secondary metabolite that would induce the antimicrobial activity.…”

Section: Resultsmentioning

confidence: 99%

Phylogenetic identification of epibiotic bacteria possessing antimicrobial activities isolated from red algal species of Japan

Kanagasabhapathy

Sasaki

Nagata

2008

World J Microbiol Biotechnol

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We investigated the diversity of epibiotic bacteria possessing antimicrobial activity isolated from nine species of red algae, and identified their phylogenetic position. For the isolation of epibiotic bacteria, nine species of red algae, Pachymeniopsis lauceolata, Plocamium telfairiae, Gelidium amansii, Chondrus oncellatus, Grateloupia filicina, Ceramium kondoi, Lomentaria catenata, Schizymenia dubyi and Porphyra yezoensis, were collected from the intertidal zone of Awaji Island, Japan. In total 92 bacteria were collected from the above red algal species. Primary screening results using disc diffusion assay revealed that 33% of bacteria possess antibacterial activity. Ten bacteria that showed high antibacterial activity were further studied for their ability to inhibit a set of fouling bacteria, some luminescent Vibrio and Photobacterium species and a panel of pathogenic bacteria. In general, the inhibitory activities were high against fouling and luminescent bacteria, while low against various pathogenic bacteria tested. These results suggest that some epibiotic bacteria have adapted to defend their position in their surface environment through the production of antibacterial metabolites giving defense against a broad spectrum of bacterial competitors. The phylogenetic analysis using 16 S rRNA sequences identified 7 of the 10 strains as belonging to the genus Bacillus, and other strains each 1 belonging to genus Microbacterium, Psychrobacter, and Vibrio species.

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Section: Resultsmentioning

confidence: 99%

Phylogenetic identification of epibiotic bacteria possessing antimicrobial activities isolated from red algal species of Japan

Kanagasabhapathy

Sasaki

Nagata

2008

World J Microbiol Biotechnol

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“…The low sequence similarity and phylogenetic analysis suggested that it might belong to a novel taxon. Some genera, to which the novel isolates belong, are well-known and prolific metabolite producers (Iwatsuki et al 2006;Wicke et al 2000). The novel strain may produce a number of commercially interesting and potentially useful products.…”

Section: Discussionmentioning

confidence: 99%

Phylogenetic Diversity and Antibacterial Activity of Culturable Fungi Derived from the Zoanthid Palythoa haddoni in the South China Sea

Qin

Yang

et al. 2014

Mar Biotechnol

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Investigation on diversity of culturable fungi mainly focused on sponges and corals, yet little attention had been paid to the fungal communities associated with zoanthid corals. In this study, a total of 193 culturable fungal strains were isolated from the zoanthid Palythoa haddoni collected in the South China Sea, of which 49 independent isolates were identified using both morphological characteristics and internal transcribed spacer (ITS) sequence analyses. Thirty-five strains were selected for phylogenetic analysis based on fungal ITS sequences. The results indicated that 18 genera within eight taxonomic orders of two phyla (seven orders of the phylum Ascomycota and one order of the phylum Basidiomycota) together with one unidentified fungal strain have been achieved, and Cladosporium sp. represented the dominant culturable genus. Particularly, 14 genera were isolated from a zoanthid for the first time. The antibacterial activities of organic extracts of mycelia and fermentation broth of 49 identified fungi were evaluated, and 29 (59.2 %) of the isolates displayed broad-spectrum or selective antibacterial activity. More interestingly, more than 60 % of the active fungal strains showed strong activity against two aquatic pathogenic bacteria Nocardia brasiliensis and Vibrio parahaemolyticus, compared with other pathogenic bacteria, indicating that zoanthid-derived fungi may protect its host against pathogens. This is the first report of systematically phylogenetic diversity and extensively antibacterial activity of zoanthid-derived fungi.

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“…(260), while a glycoglycerolipid produced by a Halichondria panicea-derived Microbacterium sp. had antitumor properties (463). In another study, several quinolones, including one with both antimicrobial and cytotoxic activities, were isolated from a pseudomonad from the Pacific sponge Homophymia sp.…”

Section: Methods For Accessing the Hidden Chemistry Of Marine Spongesmentioning

confidence: 99%

Sponge-Associated Microorganisms: Evolution, Ecology, and Biotechnological Potential

Taylor

Radax

Steger

et al. 2007

Microbiol Mol Biol Rev

1,295

1,512

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SUMMARY Marine sponges often contain diverse and abundant microbial communities, including bacteria, archaea, microalgae, and fungi. In some cases, these microbial associates comprise as much as 40% of the sponge volume and can contribute significantly to host metabolism (e.g., via photosynthesis or nitrogen fixation). We review in detail the diversity of microbes associated with sponges, including extensive 16S rRNA-based phylogenetic analyses which support the previously suggested existence of a sponge-specific microbiota. These analyses provide a suitable vantage point from which to consider the potential evolutionary and ecological ramifications of these widespread, sponge-specific microorganisms. Subsequently, we examine the ecology of sponge-microbe associations, including the establishment and maintenance of these sometimes intimate partnerships, the varied nature of the interactions (ranging from mutualism to host-pathogen relationships), and the broad-scale patterns of symbiont distribution. The ecological and evolutionary importance of sponge-microbe associations is mirrored by their enormous biotechnological potential: marine sponges are among the animal kingdom's most prolific producers of bioactive metabolites, and in at least some cases, the compounds are of microbial rather than sponge origin. We review the status of this important field, outlining the various approaches (e.g., cultivation, cell separation, and metagenomics) which have been employed to access the chemical wealth of sponge-microbe associations.

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Production and Structure Elucidation of Glycoglycerolipids from a Marine Sponge-Associated Microbacterium Species

Cited by 63 publications

References 20 publications

Phylogenetic identification of epibiotic bacteria possessing antimicrobial activities isolated from red algal species of Japan

Phylogenetic identification of epibiotic bacteria possessing antimicrobial activities isolated from red algal species of Japan

Phylogenetic Diversity and Antibacterial Activity of Culturable Fungi Derived from the Zoanthid Palythoa haddoni in the South China Sea

Sponge-Associated Microorganisms: Evolution, Ecology, and Biotechnological Potential

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