2018
DOI: 10.1016/j.ejmp.2018.10.018
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Production of Ga-68 with a General Electric PETtrace cyclotron by liquid target

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Cited by 33 publications
(38 citation statements)
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“…[30] Small amounts of various chelating Cu, Co, and Mn radionuclidic impurities are also commonly found in the cyclotron-irradiated samples of zinc solutions. [13] In contrast to Fe extraction, Cu was extracted only at 0.04%, and no detectable extraction was observed for Mn and Co.…”
Section: Co-extraction Of Other Metalsmentioning
confidence: 90%
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“…[30] Small amounts of various chelating Cu, Co, and Mn radionuclidic impurities are also commonly found in the cyclotron-irradiated samples of zinc solutions. [13] In contrast to Fe extraction, Cu was extracted only at 0.04%, and no detectable extraction was observed for Mn and Co.…”
Section: Co-extraction Of Other Metalsmentioning
confidence: 90%
“…If required, any additional purification can be performed downstream the primary recirculation loop using one of the SPE-based purification protocols described elsewhere. [11][12][13] When compared to the existing methods of 68 Ga productions using liquid targets, the ability of the continuous process to recycle 68 Zn on the fly could translate into significant savings. With the current 68 Zn prices at~$1/mg, one can expect to reduce the price of a batch by $200-$700.…”
Section: Advantages Limitations and Further Development Of Lle In Flowmentioning
confidence: 99%
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“…The diluted target solution is automatically loaded onto the cassette by nitrogen overpressure. The process is based on the 2-column approach we have previously reported for liquid targets (Nair et al 2017) and recently repeated by Riga and colleagues (Riga et al 2018). The process is shown in Figure 4.…”
Section: Chemical Isolation On the Fastlab 221 Delivery To The Fastlabmentioning
confidence: 99%
“…It should be noted that, unlike in case of 52g Mn, these elaborate and lengthy separation techniques are not adequate to isolate the short‐living manganese PET isotopes 52m Mn and 51 Mn, if produced via a solid chromium target. The development of a suitable liquid target enabling fast separation by solid phase extraction technology might provide a solution (a similar discussion is ongoing regarding the cyclotron production of 68 Ga) …”
Section: Relevant Pet Radionuclides Of Manganese For Medical Imagingmentioning
confidence: 99%