Production of gibberellic acid by fungal mycelium immobilized in sodium alginate

Kahlon, S. S.; Malhotra, Sangeeta

doi:10.1016/0141-0229(86)90121-3

Cited by 30 publications

(5 citation statements)

References 13 publications

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“…It is known that physiological factors considerably influence the GA 3 production in submerged fermentation [3,6]. To improve the yield of GA 3 in the production medium, growth parameters including pH, temperature, incubation time and media were optimized.…”

Section: Physiological Optimizationmentioning

confidence: 99%

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Improved Production of Gibberellic Acid by <i>Fusarium moniliforme </i>

Rangaswamy¹

2012

MICROBIOLOGY

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Optimization studies for improvement in the yield of gibberellic acid production by Fusarium moniliforme in submerged and solid-state fermentation is the focus of this paper. In the current study, use of jatropha seed cake as substrate for solid-state fermentation resulted in an unprecedented gibberellic acid yield of 105 mg/g of moldy bran. A 2.5 fold increased in the titre resulting in 15 g gibberellic acid /L could also be obtained by optimization of physiological parameters in submerged fermentation. This is the first study reporting such high yield of gibberellic acid and presenting a commercially viable production process using cheap substrates.

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Section: Physiological Optimizationmentioning

confidence: 99%

“…It affects stem elongation, elimination of dormancy, flowering, sex expression, enzyme induction and leaf and fruit senescence. GA 3 is a high valued industrially important biochemical with various applications in agriculture with price ranging around $ 25/g in the international market [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

Improved Production of Gibberellic Acid by <i>Fusarium moniliforme </i>

Rangaswamy¹

2012

MICROBIOLOGY

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“…It was observed that GA yield was maximized at pH 5.0 by F. moniliforme, although no significant differences were observed between the yields obtained at pH 5.0 and 5.5 on the days 6 and 7 of fermentation and pH 5.5 by A. niger. This corresponds with the studies of Kahlon and Mahlotra (1986), Shukla et al (2005), Bilkay et al (2010) and Kobomoje et al (2013) who reported maximum GA yields between pH 5.0 and 5.5.…”

Section: Resultsmentioning

confidence: 99%

Gibberellic Acid Production by Fusarium moniliforme and Aspergillus niger Using Submerged Fermentation of Banana Peel

Omojasola

Adejoro

2018

Not Sci Biol

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The present study aimed to produce gibberellic acid through fermentation using banana (Musa sapientum) peel waste as substrate. Banana peel, a domestic and industrial waste, constitutes a potential source of cheap fermentable substrate for the production of other value-added products. Fusarium moniliforme ATCC 10052 and Aspergillus niger CBS 513.88 were used as fermenting organisms. The substrate was dried, ground and its proximate composition determined. The powdered substrate was added to a modified CzapekDox broth (a semisynthetic medium), with Carboxyl methylcellulose (CMC) as control. The fermentation conditions were: pH 5.5; inoculum size 1% (5 × 10 5 spores/mL F. moniliforme) (2 × 10 6 spores/mL A. niger); substrate concentration 2 g; temperature 25 ± 2 o C; fermentation time 7 days. The fermentation was optimized by varying pH, inoculum size, substrate concentration and fermentation time. The extracted GA was subjected to infra-red spectroscopy using FT-IR. The parameters which gave the highest GA yields were thereafter combined in a single fermentation. The results of proximate analysis of banana peel substrate revealed 8.65% moisture, 9.54% protein, 5.40% lipids, 11.45% ash, 22.34% crude fibre, and 42.62% carbohydrate. The GA yields of 13.55 g/L and 12.44 g/L were produced from the banana peel substrate and 3.62 and 2.61 g/L from the CMC control by F. moniliforme and A. niger respectively. Under optimized conditions, F. moniliforme produced 17.48 g/L GA, while A. niger produced 13.50 g/L. Extracted GA was similar to standard GA sample and the present results support the potential use of banana peel for fermentative GA production.

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“…Any at-tempt to reduce the cost of production of GA 3 will be of immense value because reduction in cost will lead to its wider application to a variety of crops. It was stressed by Kahlon and Malhotra (1986) that much can be gained by producing GA 3 indigenously in India.…”

Section: Resultsmentioning

confidence: 99%

Screening and Development of Effective Mutants of Fusarium fujikuroi for enhanced Gibberellic Acid Production

2020

MAJ

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Production of gibberellic acid by fungal mycelium immobilized in sodium alginate

Cited by 30 publications

References 13 publications

Improved Production of Gibberellic Acid by <i>Fusarium moniliforme </i>

Improved Production of Gibberellic Acid by <i>Fusarium moniliforme </i>

Gibberellic Acid Production by Fusarium moniliforme and Aspergillus niger Using Submerged Fermentation of Banana Peel

Screening and Development of Effective Mutants of Fusarium fujikuroi for enhanced Gibberellic Acid Production

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