Production of natural edible melanin by Auricularia auricula and its physicochemical properties

Sun, Shujing; Zhang, Xiaojuan; Chen, Wenxing; Zhang, Liaoyuan; Zhu, Hu

doi:10.1016/j.foodchem.2015.09.069

Cited by 55 publications

(47 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…During the optimization experiments to enhance the production of melanin by Auricularia auricula, it was observed that soluble starch, tyrosine, peptone, CaCO 3 , and K 2 HPO 4 had positive effects, while glucose, (NH 4 ) 2 SO 4 , MgSO 4 , CuSO 4 , and FeSO 4 negatively impacted melanin production [46]. In other study with A. auricula, it was observed that yeast extract, tyrosine, and lactose have significant effects on pigment production and the optimization of medium resulted in 2.14-fold higher melanin concentration than that of the unoptimized medium [65].…”

Section: Factors Influencing the Melanin Productionmentioning

confidence: 88%

Production of Melanin Pigment by Fungi and Its Biotechnological Applications

Sponchiado¹,

Sousa²,

Andrade³

et al. 2017

Melanin

View full text Add to dashboard Cite

Production of the microbial pigments is one of the emerging fields of research due to a growing interest of the industry for safer products, easily degradable and eco-friendly. Fungi constitute a valuable source of pigments because they are capable of producing high yields of the substance in the cheap culture medium, making the bioprocess economically viable on the industrial scale. Some fungal species produce a dark-brown pigment, known as melanin, by oxidative polymerization of phenolic compounds, such as glutaminyl-3,4-dihydroxybenzene (GDHB) or catechol or 1,8-dihydroxynaphthalene (DHN) or 3,4-dihydroxyphenylalanine (DOPA). This pigment has been reported to act as "fungal armor" due to its ability to protect fungi from adverse conditions, neutralizing oxidants generated in response to stress. Apart from the scavenging activity, melanin exhibits other biological activities, including thermoregulatory, radio-and photoprotective, antimicrobial, antiviral, cytotoxic, anti-inflammatory, and immunomodulatory. Studies have shown that the media composition and cultivation conditions affect the pigment production in fungi and the manipulation of these parameters can result in an increase in pigment yield for large-scale pigment production. This chapter presents a comprehensive discussion of the research on fungal melanin, including the recently discovered biological activities and the potential use of this pigment for various biotechnological applications in the fields of biomedicine, dermocosmetics, materials science, and nanotechnology.

show abstract

Section: Factors Influencing the Melanin Productionmentioning

confidence: 88%

Production of Melanin Pigment by Fungi and Its Biotechnological Applications

Sponchiado¹,

Sousa²,

Andrade³

et al. 2017

Melanin

View full text Add to dashboard Cite

show abstract

“…temperature, pH, the presence of oxygen and aeration, light, stress and irradiation during cultivation, can greatly affect the cell growth and pigment biosynthesis, and should be carefully considered. Some statistic tools such as the Taguchi method, the Plackett-Burman design, or the Response surface methodology are usually used to design multifactorial experiments and to evaluate the impact of each factor in the production process (Surwase et al 2013;Saini and Melo 2015;Sun et al 2016;El-Naggar and El-Ewasy 2017). Previously, most melanin-related studies involving other microorganisms, such as Aspergillus carbonarius or Streptomyces glaucescens NEAE-H (El-Naggar and El-Ewasy 2017), could not achieve melanin suitable for industrial application yields (< 1 g L −1 medium) even after optimizing the growth conditions.…”

Section: Melanin Production By Microorganismsmentioning

confidence: 99%

Microbial production of melanin and its various applications

Tran-Ly

Reyes

Schwarze

et al. 2020

World J Microbiol Biotechnol

131

View full text Add to dashboard Cite

Melanins are natural biopolymers that are known to contribute to different biological processes and to protect organisms from adverse environmental conditions. During the past decade, melanins have attracted increasing attention for their use in organic semiconductors and bioelectronics, drug delivery, photoprotection and environmental bioremediation. Although considerable advances in these fields have been achieved, real-world applications of melanins are still scarce, probably due to the limited and expensive source of natural melanin. Nevertheless, recent biotechnological advances have allowed for relatively large-scale production of microbial melanins, which could replace current commercial melanin. In this review, we first describe different melanin sources and highlight the advantages and disadvantages of each production method. Our focus is on the microbial synthesis of melanins, including the methodology and mechanism of melanin formation. Applications of microbial melanins are also discussed, and an outlook on how to push the field forward is discussed.

show abstract

“…Exo- and endomelanin complex of Inonotus obliquus and Phellinus robustus in submerged conditions demonstrate high-antioxidant and genoprotective properties (Bisko et al 2002, 2007). Melanin in Auricularia auricula has been studied extensively (Zou et al 2010; Bin et al 2012; Zhang et al 2015; Sun et al 2016a). Melanin is found useful in the field of material science as coating material in electronic/bioelectronics, drug delivery and cosmetics as sunscreens, emphasising the importance of finding good, non-toxic melanin sources (Blumenberg 2017).…”

Section: Introductionmentioning

confidence: 99%

Purification and characterisation of a sulphur rich melanin from edible mushroom Termitomyces albuminosus Heim

2018

View full text Add to dashboard Cite

Production, purification and characterisation of a black pigment from Termitomyces albuminosus as melanin is reported, for the first time, from shaken submerged culture condition using scanning electron microscopy (SEM), elemental analysis, ultraviolet–visible (UV-VIS), and Fourier transformed infrared spectroscopy (FTIR), electron paramagnetic resonance (EPR) and 13C (CP/MAS) NMR spectra. SEM results on T. albuminosus revealed nanogranular nature of melanin nanoparticles within size range of 400–100 nm with fractal dimension D = 1.195–1.73. Elemental analysis of melanin indicated 54.6% C, 3.5% H, 2.4% N, 26.9% O, and 12% S. UV-VIS and FTIR spectra confirmed to the characteristic of melanin and were identical to the reference commercial sepia melanin. Further validation of the identity of pigment as melanin was achieved by EPR analysis. Termitomyces albuminosus melanin is postulated to be DOPA-type melanin confirmed by 13C (CP/MAS) NMR spectral analysis showing chemical shift at 200–170 ppm carbonyl, 160–110 ppm aromatic region, and with high 40–30 ppm open chain aliphatic region. Chemical modification through oxidation and cysteinylation (Pheomelanin) is implied as indicated by relatively high sulphur content (12%).

show abstract

Production of natural edible melanin by Auricularia auricula and its physicochemical properties

Cited by 55 publications

References 27 publications

Production of Melanin Pigment by Fungi and Its Biotechnological Applications

Production of Melanin Pigment by Fungi and Its Biotechnological Applications

Microbial production of melanin and its various applications

Purification and characterisation of a sulphur rich melanin from edible mushroom Termitomyces albuminosus Heim

Contact Info

Product

Resources

About