Production of γ-decalactone and 4-hydroxy-decanoic acid in the genus Sporidiobolus

Dufossé, Laurent; Féron, Gilles; Mauvais, Geneviève; Bonnarme, Pascal; Durand, Alain; Spinnler, Henry-Éric

doi:10.1016/s0922-338x(98)80056-1

Cited by 31 publications

(19 citation statements)

References 10 publications

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“…However, this reaction is not total, and some of the acid is not transformed into -decalactone. Similar results were obtained by Dufossé et al [17] and Feron et al [18], who found that acidiWcation of the cultures to pH 2.0 enhanced the recovery of -decalactone produced by Sporidiobolus ruinenii.…”

Section: Resultssupporting

confidence: 89%

The use of Macronet resins to recover γ-decalactone produced by Rhodotorula aurantiaca from the culture broth

Alchihab

Aldric

Aguedo

et al. 2009

J Ind Microbiol Biotechnol

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During the biotransformation of castor oil into gamma-decalactone, R. aurantiaca produced both the lactone form and its precursor (4-hydroxydecanoic acid). After six days of culture, a maximum yield of gamma-decalactone of 6.5 g/l was obtained. The parameters of gamma-decalactone adsorption on three Macronet resins (MN-202, MN-102 and MN-100) were investigated in water. Adsorption isotherms of gamma-decalactone for the three Macronet resins were linear. The trapping of gamma-decalactone produced by R. aurantiaca on these resins was then carried out. gamma-Decalactone was effectively retained by all the studied Macronet resins. The resin MN-202 trapped gamma-decalactone more efficiently than MN-102 and MN-100. The percentages of gamma-decalactone adsorbed on the resins MN-202, MN-102 and MN-100 were, respectively, 85, 75 and 81%, whereas around 70% of the adsorbed gamma-decalactone was then desorbed. We propose an industrial process that uses Macronet resins to extract gamma-decalactone from culture broth of R. aurantiaca.

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Section: Resultssupporting

confidence: 89%

The use of Macronet resins to recover γ-decalactone produced by Rhodotorula aurantiaca from the culture broth

Alchihab

Aldric

Aguedo

et al. 2009

J Ind Microbiol Biotechnol

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“…This was also demonstrated in plants [3] (Fig. Sporidiobolus salmonicolor and Sporidiobolus ruinenii were able to produce a signi¢cant amount of lactone, in contrast to Sporidiobolus johnsonii and Sporidiobolus pararoseus which actively metabolized this compound but did not synthesize it [8,9]. Following Okui's work, the ability of some yeasts to convert castor oil and its derivatives was industrially developed, especially for the production of one intermediate of ricinoleic acid breakdown identi¢ed as 4-hydroxy decanoic acid lactone (Q-C 10 ) by Okui [2] and usable in the food industry because of its peach-like odor [5].…”

Section: Introductionmentioning

confidence: 85%

“…Previous studies done in our lab showed that di¡erent species of the yeast Sporidiobolus showed di¡erent capacities to produce Q-C 10 from ricinoleic acid methyl ester [6,7]. Sporidiobolus salmonicolor and Sporidiobolus ruinenii were able to produce a signi¢cant amount of lactone, in contrast to Sporidiobolus johnsonii and Sporidiobolus pararoseus which actively metabolized this compound but did not synthesize it [8,9]. These di¡erences undoubtly have a metabolic origin.…”

Section: Introductionmentioning

confidence: 89%

Metabolism of ricinoleic acid into γ-decalactone: β-oxidation and long chain acyl intermediates of ricinoleic acid in the genus Sporidiobolus sp.

Blin-Perrin¹

2000

FEMS Microbiology Letters

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In order to study differences in γ‐decalactone production in yeast, four species of Sporidiobolus were cultivated with 5% of methyl ricinoleate as the lactone substrate. In vivo studies showed different time courses of intermediates of ricinoleic acid breakdown between the four species. In vitro studies of the β‐oxidation system were conducted with crude cell extracts of Sporidiobolus spp. and with ricinoleyl‐CoA (RCoA) as substrate. The β‐oxidation was detected by measuring acyl‐CoA oxidase, 3‐hydroxyacyl‐CoA dehydrogenase activities, and acetyl‐CoA production. The time courses of the CoA esters resulting from RCoA breakdown by crude extract of Sporidiobolus spp. permit the proposal of different metabolic models in the yeast. These models explained the differences observed during in vivo studies.

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“…Studies done in our lab showed that different species of the yeast Sporidiobolus (S.) cultivated in the same conditions, showed different abilities to consume the ricinoleic acid methyl ester, and to release c-C 10 in the broth (Feron et al 1996(Feron et al , 1997. S. salmonicolor and S. ruinenii were able to produce c-C 10 , in opposition to S. johnsonii and S. pararoseus which consumed the precursor, but did not generate any lactone (Dufosse´et al 1998;Feron et al 1999). These differences have been investigated in greater depth by studying the catabolism of ricinoleyl-CoA (RCoA) through the time course of the production of various-chain-length acyl-CoAs for each species of Sporidiobolus (Blin-Perrin et al 2000).…”

Section: Utilisation Of B-oxidationmentioning

confidence: 99%

Yeast as an efficient biocatalyst for the production of lipid-derived flavours and fragrances

Waché

Husson

Féron

et al. 2006

Antonie Van Leeuwenhoek

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Responding to consumer' demand for natural products, biotechnology is constantly seeking new biocatalysts. In the field of hydrophobic substrate degradation, some yeast species known some years ago as non-conventional, have acquired their right to be considered as good biocatalysts. These Candida, Yarrowia, Sporobolomyces ... are now used for themselves or for their lipases in processes to produce flavours and fragrances. In this paper we present some examples of use of these biocatalysts to generate high-value compounds and discuss the new trends related to progress in the development of molecular tools or the mastering of the redox characteristics of the medium.

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Production of γ-decalactone and 4-hydroxy-decanoic acid in the genus Sporidiobolus

Cited by 31 publications

References 10 publications

The use of Macronet resins to recover γ-decalactone produced by Rhodotorula aurantiaca from the culture broth

The use of Macronet resins to recover γ-decalactone produced by Rhodotorula aurantiaca from the culture broth

Metabolism of ricinoleic acid into γ-decalactone: β-oxidation and long chain acyl intermediates of ricinoleic acid in the genus Sporidiobolus sp.

Yeast as an efficient biocatalyst for the production of lipid-derived flavours and fragrances

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