Hyperon production in e + e − annihilation provides a clean laboratory for the production of baryons and strangeness in hadronization, and can provide insight into the structure of different hyperons by comparing their production rates. Using 52 pb −1 , 805 pb −1 , and 586 pb −1 of e + e − annihilation data taken at the ψ(2S ), ψ(3770), and ψ(4160) resonances, respectively, with the CLEO-c detector, we measure for the first time the inclusive decays of these charmonium states to the− hyperons, and discuss the status of their interpretation. We also discuss the measurements of the isospin-violating decay ψ(2S ) → Λ 0 Σ 0 and the Λ 0 Σ 0 form factor