Profile and Clinical Spectrum of Congenital Heart Defects in NICU

Gupta, Akash; Abqari, Shaad; Shahab, Tabassum; Rabbani, MU; Ali, Syed S.; Firdaus, Uzma

doi:10.21276/iabcr.2016.2.2.5

Cited by 4 publications

(3 citation statements)

References 7 publications

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“…In our study Tetralogy of Fallot was the most common cyanotic structural heart defect with frequency of 25.3%. This observation is consistent with different studies conducted in Jordan 11,12 , India 13,14,4 , Pakistan 15,16 , and globally. 17 TGA was the most common CCHD in neonatal period (27.9%) in a study conducted in Srinagar.…”

Section: Resultssupporting

confidence: 93%

Spectrum of cyanotic congenital heart disease in full term neonates attending paediatric cardiology clinic of a Tertiary Cardiac Care Centre.

Javed

Mughal

Ahmad

et al. 2022

TPMJ

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Objective: To determine the spectrum of cyanotic congenital heart disease (CCHD) in full term neonates attending paediatric cardiology clinic of a tertiary cardiac care centre. Study Design: Descriptive Cross-sectional study. Setting: Department of Paediatric Cardiology, Faisalabad Institute of Cardiology (FIC), Faisalabad. Period: January 2021 to June 2021. Material & Methods: All full term newborn of any gender with age range from day one to twenty eight days, presenting in emergency or out patient department of the institute and diagnosed as a case of CCHD at Faisalabad Institute of Cardiology on the basis of echocardiography were included in the study.The leading or main anatomical diagnosis of hemodynamically significance was adopted. The spectrum of CCHD was assessed by descriptive analysis. Results: A total of 87 patients were enrolled. Mean age was 15.7±7.98 days. There were 55.2% (n=48) male and 44.8% female (n=39) patients. Majority of patients (62.1%) presented as an emergency. Most CCHDs were of decreased pulmonary blood flow (69%, n=60). Tetralogy of Fallot was the most common CCHD seen in 25.3% neonates (n=22) followed by Transposition of great arteries (23%, n=20) and pulmonary atresia (18.4%, n=16). Ebstein anomaly of tricuspid valve was the least common CCHD (2.3%). Conclusion: Tetralogy of Fallot is the most common cyanotic congenital heart disease followed by TGA while Ebstein anomaly is the least common.

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Section: Resultssupporting

confidence: 93%

Spectrum of cyanotic congenital heart disease in full term neonates attending paediatric cardiology clinic of a Tertiary Cardiac Care Centre.

Javed

Mughal

Ahmad

et al. 2022

TPMJ

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“…Combining pulse oximetry with clinical examination can enhance the clinician's ability to detect life-threatening CHD in a timely manner. Heart murmur, central cyanosis and major congenital abnormalities were found statistically higher in the neonates with cardiac disorder [3,4].…”

Section: Introductionmentioning

confidence: 85%

Incidence of Congenital heart disease among the neonates in neonatal intensive care unit of a tertiary care hospital

et al. 2017

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Background: A large number of newborns are affected by congenital heart diseases, which accounts for a high proportion of infant mortality worldwide. But there are regional variations in the prevalence and distribution pattern of congenital heart diseases. We evaluated the incidence, risk factors and diagnostic clues for congenital heart disease in newborns in our neonatal intensive care unit. Methods: A prospective observational study was conducted in the neonatal intensive care unit of Vydehi institute of medical sciences between January 2013 to December 2016. Congenital heart disease was suspected if clinical and confirmed by 2D echocardiography and doppler and colour flow imaging. Data was collected on a predesigned proforma containing information regarding gender, gestational age and weight at birth, family history, and associated malformations. Results: Out of 1974 babies screened for CHDs, 126 babies had CHDs (4.6%) of which 71(56%) were males. Most of neonates presented with Respiratory distress (52.3%), murmurs (49.5%), abnormal chest X ray (27.7%), followed by cyanosis (18.2%) in Cyanotic CHDs(100% of the cases). Conclusion: The incidence of CHD in newborns at the neonatal intensive care unit was higher than that in all live births.VSD was the most common congenital heart defect detected while Tetralogy of Fallot was commonest among the cyanotic heart defects.

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“…A second cycle of treatment is indicated if the first one fails to close the DA. Several studies comparing the safety and efficacy of indomethacin versus ibuprofen demonstrated equal efficacy in DA closure in preterm infants [9]. However, there are studies showing shorter duration of ventilatory support, fewer cases of Necrotizing enterocolitis (NEC) and a lower incidence of oliguria in the ibuprofen group [10,11].…”

Section: Introductionmentioning

confidence: 99%

Patent ductus arteriosus – clinical profile and outcome after treatment in a tertiary care hospital

Prithviraj

Reddy²,

Subramaniam³

et al. 2017

Int J Pediatr Res

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Background: Patent ductus arteriosus (PDA) is the commonest congenital heart disease seen in neonatal ICU. Methods: A prospective observational study was conducted in the neonatal intensive care unit of Vydehi institute of medical sciences between January 2013 to December 2016. Neonates suspected to have congenital heart disease in the NICU on the basis of history clinical examination, pulse oximetry, chest X ray were included in the study and confirmed by 2D echocardiography and colour Doppler study. PDA if found hemodynamically significant treated with a three-day course of Ibubrufen and data analyzed. Results: A total of 2658 cases were admitted in the NICU during the study period of which 1974 cases were screened for CHDs. Out of 1974 babies, Echo done showed 65 babies had PDA. Out of 65 cases with PDA 32 were hemodynamically significant. About 25 out of 32 cases had responded to treatment with Ibubrufen. Ductus were closed in 5 out of 9 large PDAs. About 48% of the PDAs were closed by 5 th day of starting the treatment. Conclusion: The study shows PDA is a commonest Acyanotic CHD in NICU and early administration of the drug is helpful in closure, avoiding surgical correction later and also mortality.

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Profile and Clinical Spectrum of Congenital Heart Defects in NICU

Cited by 4 publications

References 7 publications

Spectrum of cyanotic congenital heart disease in full term neonates attending paediatric cardiology clinic of a Tertiary Cardiac Care Centre.

Spectrum of cyanotic congenital heart disease in full term neonates attending paediatric cardiology clinic of a Tertiary Cardiac Care Centre.

Incidence of Congenital heart disease among the neonates in neonatal intensive care unit of a tertiary care hospital

Patent ductus arteriosus – clinical profile and outcome after treatment in a tertiary care hospital

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