Profile of Lung Cancer Patients at Tertiary Care Hospital of North India

Abstract

BACKGROUNDCancer is a leading cause of death worldwide and lung cancer is the most common cancer in men. The aim of this study was to study the profile of patients of lung or pleural tumour and their cyto-histopathological type reporting to Department of Respiratory Diseases of GSVM Medical College, Kanpur. MATERIALS AND METHODSA total of 147 patients were included in the study. Patients were subjected to detailed history and general and systemic examination. Radiological investigations were reviewed and repeated as per requirement. Computed tomography/ Ultrasonography guided lung biopsy was done in peripherally located lesion and bronchoscopy guided procedures were performed in centrally located lesions. All histological and cytological results were noted. RESULTSIn this study, 65 patients (44.20%) were diagnosed as squamous cell carcinoma and 58 patients (39.4%) were as adenocarcinoma. 14 patients (9.5%) as small cell carcinoma, 4 patients (2.74%) as large cell carcinoma, 3 patients (2.04%) as adenosquamous cell carcinoma and 3 patients (2.04%) as pleural mesothelioma. There was higher prevalence of squamous cell carcinoma among male patients (45.2%) as compared to adenocarcinoma (40%), while this ratio was reversed in case of female patients (adenocarcinoma 46.8% and squamous cell carcinoma 31.2%). There was higher incidence of small cell carcinoma in females (21.8%) as compared to males (6%). CONCLUSIONSquamous cell carcinoma is still the most common histological type of lung cancer in male. There was relatively increased frequency of adenocarcinoma in our study as compared to other studies from India. Lung cancer is the most common cancer in men worldwide and though incidence rates is lower in females still is now the fourth most frequent cancer of women and second most common cause of death from cancer in them (GLOBOCAN 2008 cancer fact sheet). [1] Incidence rates are reportedly rising in newly industrialised and developing countries like China and India. KEYWORDS