Survival after decompressive hemicraniectomy was better than previously reported using medical management alone. A vegetative state was avoided and functional independence was possible, especially in younger patients. Increasing age was a statistically significant predictor of disability and long-term functional dependence.
<p class="abstract"><strong>Background:</strong> Cutaneous tuberculosis constitutes 1.5% of extra pulmonary tuberculosis and the disease continues to be a challenging one because of its multifaceted presentation. The present study was done to document the most common type of cutaneous tuberculosis, atypical presentations if any and response to directly observed therapy short course (DOTS)<span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> All patients with clinically suspected cutaneous tuberculosis attending outpatient department of dermatology in our hospital from October 2012 to April 2016 were included in the study. A detailed history of presenting illness and thorough general, systemic and cutaneous examination was carried out along with documentation of demographic details. Routine blood invetigations, biopsy and mantoux test were done. Diagnosed cases were treated with DOTS.<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 25 cases of cutaneous tuberculosis were included in the study. Most common type of cutaneous tuberculosis was lupus vulgaris. Atypical presentations noted during the study were multifocal lupus vulgaris (LV), co-existence of tuberculosis verrucosa cutis (TVC) and LV, TVC of lower lip, erythema induratum of bazin presenting as annular plaque in one case and as erythema nodosum in another case. DOTS were effective in majority of the patients<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> Cutaneous tuberculosis is multifaceted. High clinical suspicion is necessary in rare presentations. Coexistence of two or more morphological patterns can occur. Doubtful cases, 5-6weeks of therapeutic trail helps. Adequate dose is essential for good response. Second line drugs are to be considered in case of failure /clinical resistance<span lang="EN-IN">.</span></p><p> </p>
BACKGROUNDCancer is a leading cause of death worldwide and lung cancer is the most common cancer in men. The aim of this study was to study the profile of patients of lung or pleural tumour and their cyto-histopathological type reporting to Department of Respiratory Diseases of GSVM Medical College, Kanpur.
MATERIALS AND METHODSA total of 147 patients were included in the study. Patients were subjected to detailed history and general and systemic examination. Radiological investigations were reviewed and repeated as per requirement. Computed tomography/ Ultrasonography guided lung biopsy was done in peripherally located lesion and bronchoscopy guided procedures were performed in centrally located lesions. All histological and cytological results were noted.
RESULTSIn this study, 65 patients (44.20%) were diagnosed as squamous cell carcinoma and 58 patients (39.4%) were as adenocarcinoma. 14 patients (9.5%) as small cell carcinoma, 4 patients (2.74%) as large cell carcinoma, 3 patients (2.04%) as adenosquamous cell carcinoma and 3 patients (2.04%) as pleural mesothelioma. There was higher prevalence of squamous cell carcinoma among male patients (45.2%) as compared to adenocarcinoma (40%), while this ratio was reversed in case of female patients (adenocarcinoma 46.8% and squamous cell carcinoma 31.2%). There was higher incidence of small cell carcinoma in females (21.8%) as compared to males (6%).
CONCLUSIONSquamous cell carcinoma is still the most common histological type of lung cancer in male. There was relatively increased frequency of adenocarcinoma in our study as compared to other studies from India. Lung cancer is the most common cancer in men worldwide and though incidence rates is lower in females still is now the fourth most frequent cancer of women and second most common cause of death from cancer in them (GLOBOCAN 2008 cancer fact sheet). [1] Incidence rates are reportedly rising in newly industrialised and developing countries like China and India.
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