Profile of malaria in Madras

Santhanakrishnan, B. R.; Parthasarathy, A; Bhavani, C; Ramesh, Shanthi

doi:10.1007/bf02754851

Cited by 9 publications

(5 citation statements)

References 9 publications

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“…More than 150 cases of congenital malaria have been reported in world literature [6–10]. Congenital malaria presenting as neonatal sepsis and respiratory distress has been described in few reports from across the world [7–10].…”

Section: Discussionmentioning

confidence: 99%

Congenital Malaria due to Plasmodium Vivax Infection in a Neonate

Bhatia

Rajwaniya

Agrawal

2016

Case Reports in Pediatrics

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Although malaria is endemic in India, congenital malaria is not very common. Congenital malaria is a very rare condition in both endemic and nonendemic areas. We report a case of congenital malaria in a six-day-old neonate with fever and splenomegaly. The diagnosis was picked up accidentally on a peripheral smear examination. Congenital malaria should be kept as differential diagnosis of neonatal sepsis. Timely detection of this condition could lead to early diagnosis and treatment, thereby preventing neonatal mortality.

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Section: Discussionmentioning

confidence: 99%

Congenital Malaria due to Plasmodium Vivax Infection in a Neonate

Bhatia

Rajwaniya

Agrawal

2016

Case Reports in Pediatrics

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“…All these children had fever and majority had hepato-splenomegaly, anemia, and thrombocytopenia. Santhanakrishnan et al [10], reported two cases of congenital malaria diagnosed in the first four months of life in a study of 221 children with malaria. In our case malarial parasite was detected accidentally in the first seven days of life as reported earlier by Kothare et al [11].In another case, a 22day-old neonate presented with history of fever and jaundice for three days before admission, with splenomegaly, anaemia and thrombocytopenia.…”

Section: Discussionmentioning

confidence: 99%

Congenital Malaria

Saxena

Devgan

2008

Medical Journal Armed Forces India

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“…9 Prevalence is higher among infants of non-immune mothers than among those with partial immunity. 10 This is thought to be caused by the protective effect of maternally transferred antibodies on parasite multiplication in the infants of immune mothers. 4,11,12 In most cases of congenital malaria, the baby is likely to have been infected while in utero .…”

Section: Introductionmentioning

confidence: 99%

Congenital Malaria in Calabar, Nigeria: The Molecular Perspective

Oduwole

Gc²,

Odey³

et al. 2011

The American Society of Tropical Medicine and Hygiene

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Polymerase chain reaction (PCR) has been shown to be more sensitive in detecting low-level parasitemia than conventional blood film microscopy. We estimated the prevalence of congenital malaria using nested PCR amplification of the small subunit 18S RNA gene to detect low-level parasitemia and identify Plasmodium species in 204 mother–neonate pairs. Cord-blood parasitemia was detected in four babies by PCR, giving a prevalence of 2.0%. The newborns of primidgravidae were more susceptible to congenital malaria than those of multigravidae (P < 0.0001). There was a strong correlation between placental malaria and congenital malaria (odds ratio = 10.1, 95% confidence interval = 1.3–76.1, P = 0.0487). We conclude that the prevalence of congenital malaria in Calabar detected by PCR is lower than has been reported in this environment through microscopy.

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Profile of malaria in Madras

Cited by 9 publications

References 9 publications

Congenital Malaria due to Plasmodium Vivax Infection in a Neonate

Congenital Malaria due to Plasmodium Vivax Infection in a Neonate

Congenital Malaria

Congenital Malaria in Calabar, Nigeria: The Molecular Perspective

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