Profile of patients with Fournier’s gangrene and their clinical evolution

Abstract

Fournier's gangrene patients in this series had a long disease duration and a high prevalence of comorbidities, with a high mortality rate.

Fournier’s Gangrene: Review of 36 Cases

“…The patients can present with fever, malaise, local discomfort, purulent collection and sepsis. [13] The differential diagnosis includes many diseases, such as cellulitis, acute epididymitis, orchitis, strangulated hernia, scrotal abscess, balanitis, herpes infection, pyoderma gangrenosum, polyarteritis nodosa, warfarin necrosis and ecthyma gangrenosum. [6] Radiological examinations, such as X-rays, ultrasonography, computed tomography and magnetic resonance imaging techniques, may be helpful in the diagnosis when the diagnosis is uncertain.…”

“…Pathophysiologically, bacterial infection results in obliterating endarteritis, ischemia and eventually tissue necrosis. [13] There are some predisposing factors, such as age, hypertension, chronic renal disease, obesity, hepatic diseases, alcoholism, congestive heart failure, peripheral vascular disease, smoking, immunosuppression, acquired human immunodeficiency syndrome, cachexia, diabetes mellitus and malnutrition. [12][13][14] Some scoring systems were developed for the diagnosis and prognosis of FG.…”

“…[13] There are some predisposing factors, such as age, hypertension, chronic renal disease, obesity, hepatic diseases, alcoholism, congestive heart failure, peripheral vascular disease, smoking, immunosuppression, acquired human immunodeficiency syndrome, cachexia, diabetes mellitus and malnutrition. [12][13][14] Some scoring systems were developed for the diagnosis and prognosis of FG. [12] The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) scoring system includes age, gender, potassium, sodium, creatinine, platelet, C-reactive protein, leukocyte, hemoglobin and glucose.…”

Perfil dos pacientes com gangrena de Fournier utilizando a oxigenoterapia hiperbárica como tratamento adjuvante

“…Analisando os resultados, observa-se que o perfil do paciente com GF do presente estudo foi do sexo masculino, com média de idade de 55,6 anos, concordando com a literatura 2,5,10,12 .…”

“…Estudos demonstram que na GF encontram-se uma associação de bactérias aeróbicas e anaeróbicas normalmente não patogênicas, mas mortais quando em locais não habituais. Essas bactérias podem agir de forma sinérgica, contribuindo, com isso, na rápida evolução e aumento da área disseminada, agravando o quadro da doença 5,6 .…”