Profiling of 21 novel microRNA clusters and their targets in an important grain: wheat (Triticum aestivum L.)

Achakzai, Habibullah Khan; Barozai, Muhammad Younas Khan; Achakzai, Abdul Kabir Khan; Asghar, Muhammad; Din, Muhammad

doi:10.30848/pjb2019-1(35)

Cited by 4 publications

(1 citation statement)

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“…MiRNA clusters have been detected in animals and in humans but in plant infrequent miRNA clusters were observed by Yu et al, (2006) and Achakzai et al, (2019). This study focuses on the identification of mirRNA as the cluster of pre-miRNA.…”

Section: Introductionmentioning

confidence: 99%

The identification of eighteen precursor miRNA clusters and their targets in barley (Hordeum vulgare L.)

Achakzai¹,

Barozai²,

Baloch³

et al. 2018

PAK.J.BOT.

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MicroRNAs (miRNAs) are short, endogenous and non-protein coding RNAs that are 18-26 nucleotides (nt) in length. The miRNAs have been shown to play important regulatory roles in almost all plant processes, including responses to various stresses. These regulatory functions of the miRNAs are to negatively control the protein coding sequences at posttranscriptional level. The mature miRNAs (18-26 nt) are generated from long (50-550 nt) precursor miRNAs (pre-miRNAs). Mostly the pre-miRNAs have one mature miRNA sequence in the stem region, but few have been reported with more than one mature miRNAs. Such miRNAs are called pre-miRNA cluster. In current research, various computational tools were used for the identification and characterization of new conserved pre-miRNA clusters and their targets in barley (Hordeum vulgare L.). Consequently, a total 18 new pre-miRNA clusters were identified from 17 miRNAs families in barley from total 501,838 express sequence tags (ESTs).

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Section: Introductionmentioning

confidence: 99%