Profiling of iridoid glycosides in Vaccinium species by UHPLC-MS

Minutifloroside, a New Bis-Iridoid Glucoside with Antifungal and Antioxidant Activities and Other Constituents from Palicourea minutiflora

“…[16][17][18][19][20][21][22][23][24][25] The structure of the new compound 1 was elucidated by spectrometric methods, including 1D and 2D NMR experiments and HRESIMS. 28 It was also observed that the ion of m/z 389.1084 ([C 16 H 21 O 11 ] -) fragmented by water loss to the ion of m/z 371.0978. 26,28 The fragment of m/z 227.0556 may be formed from the precursor ion and the product ion of m/z 389.1084.…”

“…28 It was also observed that the ion of m/z 389.1084 ([C 16 H 21 O 11 ] -) fragmented by water loss to the ion of m/z 371.0978. 26,28 The fragment of m/z 227.0556 may be formed from the precursor ion and the product ion of m/z 389.1084. 28,29 This ion presents several fragments, providing more information of the structure resulting in two possible ions pathways, one by its decarboxylation resulting in the ions of m/z 183.0657 ([C 9 H 11 O 4 ] -) and the other fragment of m/z 209.0450 ([C 10 H 9 O 5 ] -) was formed by elimination of a water.…”

“…26,28 The fragment of m/z 227.0556 may be formed from the precursor ion and the product ion of m/z 389.1084. 28,29 This ion presents several fragments, providing more information of the structure resulting in two possible ions pathways, one by its decarboxylation resulting in the ions of m/z 183.0657 ([C 9 H 11 O 4 ] -) and the other fragment of m/z 209.0450 ([C 10 H 9 O 5 ] -) was formed by elimination of a water. 28 The 1 H and 13 C NMR spectra indicated the presence of the signals of two distinct moieties of an iridoid glucoside structure and suggested this compound is a bis-iridoid glucoside which is hereafter referred to as units A and B ( Table 1) 6 in the 13 C NMR spectra.…”

“…28,29 This ion presents several fragments, providing more information of the structure resulting in two possible ions pathways, one by its decarboxylation resulting in the ions of m/z 183.0657 ([C 9 H 11 O 4 ] -) and the other fragment of m/z 209.0450 ([C 10 H 9 O 5 ] -) was formed by elimination of a water. 28 The 1 H and 13 C NMR spectra indicated the presence of the signals of two distinct moieties of an iridoid glucoside structure and suggested this compound is a bis-iridoid glucoside which is hereafter referred to as units A and B ( Table 1) 6 in the 13 C NMR spectra. In the NOESY spectrum, a signal at d 3.14 (H-9) correlated with 5.29 (H-1) and 3.04 (H-5) indicating the cis-junction between the two rings and the O-glycosyl residue C-1" with a β configuration.…”

Analysis of the chemical components of Qixianqingming granules and their metabolites in rats by UPLC‐ESI‐Q‐TOF‐MS

“…Five iridoid glycosides were successfully detected in QXQM; among them, three compounds were confirmed as ajugol, rehmannioside D, and rehmannioside A by standard reference. Compound 2 generated the deprotonated ion [M‐H] − at m / z 389, fragment ions at m / z 227 [M‐H‐glc] − , and m / z 209 [M‐H‐glc‐H 2 O] − , in line with that of deacetylasperulosidic acid . Therefore, compound 2 was unequivocally identified as deacetylasperulosidic acid.…”