Profiling of phenolic acids and flavonoids in sweet potato (Ipomoea batatas L.) leaves and evaluation of their anti-oxidant and hypoglycemic activities

Luo, Dan; Mu, Taihua; Sun, Hongnan

doi:10.1016/j.fbio.2020.100801

Cited by 59 publications

(35 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…An Acquity UHPLC BEH-C18 column (2.1 i.d. × 100 mm, 1.7 μm, Waters, USA) was used to separate polyphenols, with a gradient solvent system of 0.25% formic acid–water (elution A) and 0.25% formic acid–methanol (elution B) using the following parameters: 0–1 min, 5% B; 8 min, 25% B; 11 min, 60% B; 13 min, 100% B; 16 min, 100% B; and 16.1–20 min, 5% B. Polyphenols were identified using multiple reaction monitoring, and the basic structure of peaks were deduced by parent ions, fragment ions, and comparisons with published mass spectra (MS) data [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] . Furthermore, polyphenols were assigned by comparing the respective standards using UHPLC-MS, and their quantification was achieved by comparing the calibration curve of respective standards expressed as μg per g of dry weight of plant powder (μg/g DW).…”

Section: Methodsmentioning

confidence: 99%

Ultrasonic-assisted extraction of polyphenolic compounds from Paederia scandens (Lour.) Merr. Using deep eutectic solvent: optimization, identification, and comparison with traditional methods

Liu

Wang

Zhang

et al. 2022

Ultrasonics Sonochemistry

View full text Add to dashboard Cite

Section: Methodsmentioning

confidence: 99%

Ultrasonic-assisted extraction of polyphenolic compounds from Paederia scandens (Lour.) Merr. Using deep eutectic solvent: optimization, identification, and comparison with traditional methods

Liu

Wang

Zhang

et al. 2022

Ultrasonics Sonochemistry

View full text Add to dashboard Cite

“…were tentatively identified as rutin and luteolin-7-O-glucoside (Fan et al, 2012;Luo et al, 2021). It can be seen that chlorogenic acid is the main phenolic compound in PSPLP, which accounts for 88.3%.…”

Section: Characterization Of Psplpmentioning

confidence: 99%

“…The pharmacological evaluation of the extract of sweet potato leaves showed that sweet potato leaves had a variety of activities to promote health, such as antioxidant, antimutagenesis, anticancer, anti-diabetes, anti-inflammatory, antibacterial, and anti-tumor activities . In addition, sweet potato leaves are often processed into a variety of foods, beverages, and functional foods (Luo et al, 2021). Purple potato leaves are the main by-products of purple sweet potato, which are quite abundant in polysaccharides, polyphenols, proteins, vitamins, and minerals.…”

Section: Introductionmentioning

confidence: 99%

In vitro and in vivo ameliorative effects of polyphenols from purple potato leaves on renal injury and associated inflammation induced by hyperuricemia

Sun

Kan

Cai

et al. 2022

Journal of Food Biochemistry

View full text Add to dashboard Cite

In the present study, the ameliorative effects of polyphenols from purple potato leaves (PSPLP) on hyperuricemia were investigated. HPLC-MS analysis showed that PSPLP was mainly composed of caffeoylquinic acid derivatives (84%). PSPLP inhibited the levels of cytokines (IL-1β, IL-6, and TNFα) in monosodium urate-induced RAW264.7 cells. In vivo, PSPLP significantly inhibited the level of uric acid in hyperuricemia mice from 209.6 to 166.6 μM, and significantly interfered with the activities of xanthine oxidase (XOD) and adenosine deaminase in liver, the activity of XOD decreased from 13.5 to 11.6 U/gprot. PSPLP can decrease serum creatinine level from 105 to 59 μM, and urea nitrogen level from 21.9 to 14.1 mM, which can effectively protect kidney.These results provide a reference for future research and application of PSPLP as a functional food to intervene hyperuricemia and associated inflammation. Practical applicationsThis study evaluated the effect of polyphenols from purple potato leaves (PSPLP) on hyperuricemia. The results suggested that PSPLP has an important role in the intervention of hyperuricemia and hyperuricemic-related inflammation or renal injury, and can be used in the application of functional foods. These results provided a basis for further study on the biological activities of polyphenols from purple sweet potato leaves.

show abstract

“…The FRAP activity was measured according to a previously reported method with some modifications [30].…”

Section: Scavenging Activity(mentioning

confidence: 99%

Reflux Extraction Optimization and Antioxidant Activity of Phenolic Compounds from Pleioblastus amarus (Keng) Shell

Meng

Liu

et al. 2022

Molecules

View full text Add to dashboard Cite

Phenols were extracted from the Pleioblastus amarus (Keng) shell (PAS) using ethanol. A Plackett–Burman assessment indicated that the factors affecting polyphenol extraction included the ethanol concentration, extraction temperature, liquid to solid ratio, extraction time, and reflux extraction times; the best extraction parameters were the ethanol concentration of 75%, a 20:1 liquid to solid ratio, and an extraction time of 2.1 h. The number of polyphenols was 7.216 mg/g. Furthermore, the phenol composition analysis showed the presence of p-Coumaric acid (196.88 mg /mL) and rutin (312.9 mg /mL), which were used for the in vitro extraction and determination of the antioxidant activity. According to the A, B, C, and D antioxidant activity assays, the ethyl acetate phase was the strongest with low IC50 values of 0.169 ± 0.01 mg/mL, 0.289 ± 0.01 mg/mL, 0.372 ± 0.01 mg/mL, and 1.029 ± 0.03 mg/mL, respectively, confirming high antioxidant activity. For the n-butanol and petroleum ether phases, antioxidant activity was lower. This study showed that the polyphenol extract from Pleioblastus amarus (Keng) shell displayed excellent antioxidant activity, enhancing its practical application.

show abstract

Profiling of phenolic acids and flavonoids in sweet potato (Ipomoea batatas L.) leaves and evaluation of their anti-oxidant and hypoglycemic activities

Cited by 59 publications

References 39 publications

Ultrasonic-assisted extraction of polyphenolic compounds from Paederia scandens (Lour.) Merr. Using deep eutectic solvent: optimization, identification, and comparison with traditional methods

Ultrasonic-assisted extraction of polyphenolic compounds from Paederia scandens (Lour.) Merr. Using deep eutectic solvent: optimization, identification, and comparison with traditional methods

In vitro and in vivo ameliorative effects of polyphenols from purple potato leaves on renal injury and associated inflammation induced by hyperuricemia

Reflux Extraction Optimization and Antioxidant Activity of Phenolic Compounds from Pleioblastus amarus (Keng) Shell

Contact Info

Product

Resources

About