2020
DOI: 10.21577/0103-5053.20200093
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Profiling the Cymbopogon nardus Ethanol Extract and Its Antifungal Potential against Candida Species with Different Patterns of Resistance

Abstract: The essential oil of Cymbopogon nardus, citronella, has been extensively studied. However, the chemical and biological properties of the ethanolic extract (EE) of C. nardus have not been evaluated. The aim of this study was to characterize the chemical composition of the EE of C. nardus and its active fraction (FrD). Moreover, the cytotoxic and antifungal properties of these extracts against Candida species with different resistance profiles to conventional drugs were evaluated. The compounds identified in EE … Show more

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Cited by 2 publications
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“…The chemical compositions of hydroalcoholic extracts from different plants of the Cymbopogon genus have been described in several works [27,29,[57][58][59], but to the best of our knowledge, there are no previous studies on the chemical compositions of citronella (C. winterianus) and palmarosa (C. martinii) extracts. The analysis of lemongrass (C. citratus) extracts [60,61] found compounds in common, such as 3-caffeoyl quinic (25.2 mg/100 g dry plant), caffeic (2.94 mg/100 g plant), 4-caffeoyl quinic (3 mg/100 g plant), and 5-caffeoyl quinic (44.9 mg/100 g dry plant) acids, although the amounts found in the plants studied here were higher (Table S11).…”
Section: Discussionmentioning
confidence: 99%
“…The chemical compositions of hydroalcoholic extracts from different plants of the Cymbopogon genus have been described in several works [27,29,[57][58][59], but to the best of our knowledge, there are no previous studies on the chemical compositions of citronella (C. winterianus) and palmarosa (C. martinii) extracts. The analysis of lemongrass (C. citratus) extracts [60,61] found compounds in common, such as 3-caffeoyl quinic (25.2 mg/100 g dry plant), caffeic (2.94 mg/100 g plant), 4-caffeoyl quinic (3 mg/100 g plant), and 5-caffeoyl quinic (44.9 mg/100 g dry plant) acids, although the amounts found in the plants studied here were higher (Table S11).…”
Section: Discussionmentioning
confidence: 99%
“…Cymbopogon nardus (L.) Nardus is commonly used in perfume, cosmetic production, as an insect repellent and has antiviral activity. The main chemical constituents are geraniol, citral, citronellal, and citronellol [24]. Medicinal plants used by the community are generally based on information from generation to generation.…”
Section: Introductionmentioning
confidence: 99%