1965
DOI: 10.1016/0002-9378(65)90599-5
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Progesterone concentrations in uterine venous blood after intra-amniotic injection of hypertonic saline in midpregnancy

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Cited by 45 publications
(6 citation statements)
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“…in either abortion occurring late in gestation or normal parturition. The results in this study differ from those reported by Short, Wagner, Fuchs & Fuchs (1965), who observed an insignificant decline in progesterone levels of ovarian venous and peripheral plasma progesterone of women given intra-amniotic injections of hypertonic saline to induce abortion. However, their findings in the saline-treated women did not differ from those observed at parturition in normal women where uterine activity increases in spite of high levels of circulating progesterone.…”
Section: Discussioncontrasting
confidence: 85%
“…in either abortion occurring late in gestation or normal parturition. The results in this study differ from those reported by Short, Wagner, Fuchs & Fuchs (1965), who observed an insignificant decline in progesterone levels of ovarian venous and peripheral plasma progesterone of women given intra-amniotic injections of hypertonic saline to induce abortion. However, their findings in the saline-treated women did not differ from those observed at parturition in normal women where uterine activity increases in spite of high levels of circulating progesterone.…”
Section: Discussioncontrasting
confidence: 85%
“…The persistently high plasma concentrations at 20 hr were probably due to a continued supply of 'precursors by maternal adrenals and the presence of an intact placenta. Persistence of the plasma progesterone (30) and human chorionic gonadotropin (HCG) (8) under similar conditions attests to the viability of the placenta and supports the quantitative contribution of adrenal sources to E2 secretion at this time of pregnancy. The patient with suppressed adrenals had a fall of E2 to 200 pg/ml.…”
Section: Discussionmentioning
confidence: 67%
“…It has never been possible, however, to demonstrate convincingly any fall in pregnanediol excretion (Scott Russell, 1961) or in systemic blood (Zander, 1961) or uterine vein (Short et al, 1965) progesterone levels before labour. Nor can injections of progesterone postpone normal labour.…”
Section: Methodsmentioning
confidence: 99%