Progesterone receptor in the reproductive system of the female of Octopus vulgaris: Characterization and immunolocalization

Cosmo, Anna Di; Paolucci, Marina; Cristo, Carlo Di; Botte, Virgillo; Ciarcia, Gaetano

doi:10.1002/(sici)1098-2795(199808)50:4<451::aid-mrd9>3.3.co;2-t

Cited by 15 publications

(21 citation statements)

References 24 publications

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“…Similar to our finding, PR with molecular weight of 70 kDa was identified by Western blotting in O. vulgaris and A. pallipes (Di Cosmo et al 1998. All of the above data suggest that the occurrence of PR in invertebrates is well-conserved.…”

Section: Discussionsupporting

confidence: 90%

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The identification and distribution of progesterone receptors in the brain and thoracic ganglion in the mud crab Scylla paramamosain (Crustacea: Decapoda: Brachyura)

Huang

Song

et al. 2010

Invert Neurosci

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The existence of progesterone receptors (PR) in the Scylla paramamosain (mud crab) was studied using immunological techniques. By Western blotting, PR with an apparent molecular weight of 70 kDa is identified in both the brain and the thoracic ganglion. By immunohistochemistry, PR immunoreactive neurons are detected mainly in the protocerebrum, the subesophageal ganglion and the leg ganglion. PR immunoreactivity is localized mainly in the nuclei of these neurons, while only a few neurons show such activities in their cytoplasm. Our results provide evidence that progesterone modulates the neuroendocrine system mainly via nucleus receptors.

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Section: Discussionsupporting

confidence: 90%

“…For example, in Octopus vulgaris, PR immunoreactivity was observed in the nuclei of the follicle cells in the ovary of the proximal portion of the oviduct and of the outer region of the nidamental gland (Di Cosmo et al 1998). In Austropotamobius pallipes (crayfish), PR has also been identified in the ovary and hepatopancreas .…”

Section: Discussionmentioning

confidence: 99%

The identification and distribution of progesterone receptors in the brain and thoracic ganglion in the mud crab Scylla paramamosain (Crustacea: Decapoda: Brachyura)

Huang

Song

et al. 2010

Invert Neurosci

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“…For invertebrates an equally complex system has not been proven yet. However, the recent discovery of estrogen receptors in invertebrate taxa, both in the deuterostome and protostome clades (de Waal et al, 1982;di Cosmo et al, 2002) indicates that steroid-binding proteins and, therefore, mechanisms associated with the signal transduction process are phylogenetically very old (Thornton et al, 2003). Therefore in the present study, hsp90 was selected as a potential biomarker, particular in view to possible uncoupling effects.…”

Section: Introductionmentioning

confidence: 99%

Bisphenol A in Artificial Indoor Streams: II. Stress Response and Gonad Histology in Gammarus fossarum (Amphipoda)

et al. 2005

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The effects of the world wide-distributed chemical bisphenol A (BPA) on the endocrine system of vertebrates have been demonstrated in several studies. Here, we report on the impact of BPA (0, 5, 50 and 500 microg/l nominally, deduced effective concentrations 0, 0.24, 2.4, and 24.1 microg/l, respectively, all at 15 degrees C) on the 70 kD stress protein family (hsp70), the 90 kD stress protein family (hsp90), and gonad histology of the crustacean Gammarus fossarum exposed in artificial indoor streams. The animals were exposed for a maximum of 103 days and samples were taken at the beginning and at days 34, 69 and 103 of the experiment. Exposure to BPA resulted in accelerated maturation of oocytes in females and in a decline in the number and size of early vitellogenic oocytes. The level of hsp90, which plays a pivotal role in vertebrate sex steroid signal transduction, was significantly reduced by BPA. In all five streams, measured parameters did not indicate any captivity stress for a period of 69 days. Beyond this time, the mortality rate and proteotoxic effects, the latter measured by hsp70 expression, were found to be elevated.

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“…PRG receptor immunoreactive elements were identified in the reproductive system of the female Octopus vulgaris [90]. According to Tosti, the PRG receptors are physiologically active because the external application of PRG stimulates the activation of spermatozoa in Octopus [91].…”

Section: Sex Steroid-like Receptors In Molluscsmentioning

confidence: 99%

Pond Snail Reproduction as Model in the Environmental Risk Assessment: Reality and Doubts

Pirger¹,

Zrínyi²,

Maász³

et al. 2018

Biological Resources of Water

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In European limnetic systems, the most relevant endocrine-disrupting chemicals (EDCs) of steroid type are the natural and synthetic hormones, phytosterols, pesticides, biocides and other chemicals produced by the plastic industry. Their presence in aquatic ecosystems represents a potentially adverse environmental and public health impact. Furthermore, this is a warning signal that the current handling of pharmaceuticals needs to be further improved. Nowadays, it has become clear that EDCs have specific disturbing effects on the neuroendocrine system of invertebrate and vertebrate aquatic animals, particularly gastropods. Among a latter, pond snail (Lymnaea stagnalis) has been used as the first aquatic non-arthropod test organism in studying the effect of EDCs because they are sensitive to various anthropogenic steroids, like progestogens. Investigating a variety of reproductive endpoints of Lymnaea, such as fecundity, oocyte production, egg mass production, the quality of egg masses, the shell size in development and after egg-laying, the time window of cell division in the offspring, the metabolite content of single-cell zygotes and egg albumen has concluded that progestogen contaminations in water are detrimental for reproduction and early stage development of Lymnaea. This chapter is an attempt to show whether Lymnaea reproduction, despite many altering reproductive endpoints, is a suitable model for environmental risk assessment or not.

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Progesterone receptor in the reproductive system of the female of Octopus vulgaris: Characterization and immunolocalization

Cited by 15 publications

References 24 publications

The identification and distribution of progesterone receptors in the brain and thoracic ganglion in the mud crab Scylla paramamosain (Crustacea: Decapoda: Brachyura)

The identification and distribution of progesterone receptors in the brain and thoracic ganglion in the mud crab Scylla paramamosain (Crustacea: Decapoda: Brachyura)

Bisphenol A in Artificial Indoor Streams: II. Stress Response and Gonad Histology in Gammarus fossarum (Amphipoda)

Pond Snail Reproduction as Model in the Environmental Risk Assessment: Reality and Doubts

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