Prognose und Nachsorge mikrobiell verursachter Endokarditiden

Horstkotte, Dieter; Piper, Cornelia; Niehues, R

doi:10.1007/978-3-642-87079-8_15

Cited by 6 publications

(2 citation statements)

References 33 publications

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“…Im Fall einer Komplikation muss also individuell geprüft werden, ob zusätzlich zur konservativen medikamentösen Therapie eine dringliche chirurgische Intervention indiziert ist. Bei zahlreichen Komplikationen wird mit der chirurgischen Intervention eine signifikante Prognoseverbesserung erzielt [2,[10][11][12]16].…”

Section: Management Typischer Komplikationenunclassified

“…Dies gilt insbesondere für Vegetationen, die an den sehr mobilen Segelanteilen der Mitralklappe haften und deshalb hohen Beschleunigungen ausgesetzt sind. Vegetationen an der Mitralklappe mit > 10 mm Durchmesser bedeuten eine hohe Emboliegefahr (27% innerhalb von 10 Tagen, 76% innerhalb von 30 Tagen nach initialem Vegetationsnachweis) [9,12] und sind daher eine Operationsindikation.…”

Section: Systemische Thromboembolienunclassified

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Endokarditis: aktuelle Diagnostik und Therapie

Piper

Horstkotte

2008

Med Klin

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In patients suffering from infective endocarditis (IE), initial symptoms and clinical findings are unspecific. Physicians primarily involved should always consider IE a potential diagnosis. Any delay in diagnosis and thus in an adequate antimicrobial therapy has a significant negative prognostic influence. Any subject suspected to have IE should immediately have a transthoracic echocardiography (TTE) by an experienced examiner. If the TTE results are inconclusive, transesophageal echocardiography (TEE) has to be performed without delay. Other steps in diagnosis, medical and surgical therapy follow established and evidenced-based guidelines. Antimicrobial regimens are standardized for IE, for which demonstration of causative microorganisms from blood cultures or other microbiological sources is unavoidable. If there are problems in diagnosis, if difficult-to-treat microoganisms are isolated or difficult-to-treat situations complicate active IE, a reference center should be involved.

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Section: Management Typischer Komplikationenunclassified

Section: Systemische Thromboembolienunclassified