Prognosis for rubeosis iridis following central retinal vein occlusion.

Sinclair, Stephen H.; Gragoudas, Evangelos S.

doi:10.1136/bjo.63.11.735

Cited by 71 publications

(22 citation statements)

References 10 publications

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“…NVG rarely results from non-ischaemic vascular occlusion (3,4,11) Neovascular glaucoma is known to develop in 8% of all CRVO, and 67-82% of ischaemic CRVO (3,4,(10)(11)(12). The high prevalence of hypertension in these subjects suggest the condition to be a predisposing systemic factor associated with CRVO in this series.…”

Section: Discussionmentioning

confidence: 86%

Neovascular Glaucoma in a Nigerian African population

Ashaye

Adeoti²

2007

E Af Med Jrnl

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Objective: To determine the ocular and systemic factors associated with neovascular glaucoma (NVG) in an African population. Design: Hospital based cross sectional study. Setting: Eye clinic, Department of Ophthalmology, University College Hospital, Ibadan, Nigeria. Subjects: Sixty one consecutive patients with clinical diagnosis of NVG seen between January 1995 and December 1999 had a complete ocular evaluation. Results: Among the 61 subjects studied with an identifiable aetiological factor presumably causing neovascular glaucoma, 82% had associated posterior segment diseases producing ischaemia. These were retinal venous obstruction (78.7%), retinal arterial occlusion (1.6%). Those with no identifiable vaso-occlusive disease had couching (11.5%), aphakia with vitreous loss (3.3%) and chronic uveitis (1.6%). Systemic arterial hypertension was present in 62.3% while diabetes mellitus was present in only 8.3% of the subjects studied. Chronic uveitis and penetrating eye injury were infrequently diagnosed. Chronic open angle glaucoma was present in the other eye of 37.7% of subjects. Neovascular glaucoma was unilateral in 95.1% of subjects. 84.4% of affected eyes were blind on presentation. Males outnumbered females among subjects with NVG above 40 years, while females outnumbered males in the subjects below 40 years of age. Eyes of that were couched constitute a significant proportion of subjects with neovascular glaucoma. Conclusion: Medical conditions such as systemic hypertension, diabetes and ocular conditions like retinal vein, retinal artery occlusion, couching and glaucoma were associated with NVG. Most of these ocular and systemic associations should be identified early and treated to prevent neovascular glaucoma in the other eye of the subject.

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Section: Discussionmentioning

confidence: 86%

Neovascular Glaucoma in a Nigerian African population

Ashaye

Adeoti²

2007

E Af Med Jrnl

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“…CVOS study has reported that visual acuity outcome in CRVO was largely dependent on initial acuity. 11 Eyes with good initial vision have a good chance of maintaining excellent vision while a poor visual outcome is seen in those who had poor initial acuity.…”

Section: Crvo Groupmentioning

confidence: 99%

“…According to literature, incidence of rubeosis is 20% among CRVO. 11,12 Among ischaemic eyes, rubeosis with or without NVG occur in 45 to 80% and this usually develops by 4-7 months of the occlusion. Neovascularisation of optic disc or retina is a rare complication but has been reported in 24% of ischaemic CRVO.…”

Section: Crvo Groupmentioning

confidence: 99%

Study on Clinical Profile of Patients With Retinal Vein Occlusion

Sankaranarayanan¹,

Padmavathi²,

Nova³

et al. 2017

jemds

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“…None of the non-ischemic CRVO patients developed NVG. Neo-vascular glaucoma was seen in 67 to 82 % of the ischemic CRVOs and in 1 % of the non-ischemic CRVO in other studies (Zegarra et al, 1979;Sinclair and Gragoudas, 1979). One patient developed vitreous hemorrhage.…”

Section: Resultsmentioning

confidence: 88%

Clinico-epidemiological characteristics of central retinal vein occlusion in a tertiary level eye care center of Nepal

Shrestha

Byanju²,

Bhattarai

et al. 2014

Nep J Oph

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Background: Central retinal vein occlusion (CRVO) is one of the common retinal disorders causing severe visual impairment. Objective: To study the clinical profile, risk factors and visual outcome in central retinal vein occlusion. Materials and methods: Seventy-four eyes of 74 patients with central retinal vein occlusion were retrospectively enrolled during the period of one year. All the patients in the study were classified with regard to their ischemic status into two groups, ischemic CRVO and non-ischemic CRVO. The demographic pattern of the patients was recorded. The other parameters studied were visual acuity, history of glaucoma, hypertension, diabetes mellitus and hyperlipidemia. The patients were followed up at 1 month, 3 months and 6 months after treatment.Results: The majority of the patients (n = 49, 66.2 %) had the ischemic type of CRVO, whereas, 25 (33.8 %) of them had the non-ischemic type. The CRVO was more commonly observed in males in both the groups. Hypertension was the most common risk factor associated with CRVO. The visual improvement was significantly better in non-ischemic CRVO (RR = 0.04, 95% CI = 0.01 -0.31, p = 0.000). Conclusion:The CRVO was more common in males than in females. It was associated with systemic hypertension. The ischemic type of the CRVO was more prevalent than the non-ischemic one in this study. Visual outcome was better in the non-ischemic CRVO.

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Prognosis for rubeosis iridis following central retinal vein occlusion.

Abstract: (Smith, 1961;Vannas, 1961;Laatikainen and Kohner, 1976). The stimulus for anterior segment neovascularisation is poorly understood but is thought to be related to severe retinal ischaemia (Smith, 1961;Ashton, 1961;Shilling and Kohner, 1976

Cited by 71 publications

References 10 publications

Neovascular Glaucoma in a Nigerian African population

Neovascular Glaucoma in a Nigerian African population

Study on Clinical Profile of Patients With Retinal Vein Occlusion

Clinico-epidemiological characteristics of central retinal vein occlusion in a tertiary level eye care center of Nepal

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