Prognostic and accuracy data of multidetector CT coronary angiography in an established clinical service

Prognostic Value of Cardiac Computed Tomography Angiography

“…Our systematic review and meta-analysis is the first comprehensive analysis of multiple recent longitudinal studies describing the prognostic value of CCTA (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25). We have shown that the absence of CAD on CCTA conveys an excellent prognosis for symptomatic patients being evaluated for suspected CAD.…”

“…The abstract or full text of the 39 remaining studies were evaluated to determine eligibility. Twenty-one studies (14,15,23,25,28,(41)(42)(43)(44)(45)(46)(47)(48)(49)(50)(51)(52)(53)(54)(55)(56) were excluded after further review for reasons outlined in Figure 1. Eighteen studies were identified for inclusion from the literature search (7,8,10 -12,16 -22,24,26 -30).…”

Myocardial perfusion imaging with first-pass computed tomographic imaging: Measurement of coronary flow reserve in an animal model of regional hyperemia

“…Preliminary studies have suggested that it does serve as a prognosticator for patients being evaluated for the presence or absence of coronary artery disease. [4][5][6][7][8] Functional criteria however, whether it be wall motion by stress echocardiography or myocardial perfusion imaging by SPECT techniques, have shown incremental prognostic information when coronary anatomy is known. [18][19][20][21][22] To this end, there have been several approaches to combine CTA with an assessment of myocardial perfusion.…”

“…1,2 While invasive angiography and CTA can provide prognostic information in certain subsets of patterns of disease, [3][4][5][6][7][8] it cannot provide functional significance of disease. A number of studies have shown the incremental benefit of a measure of myocardial perfusion over and above that provided by coronary anatomy.…”

The Year in Cardiac Imaging

“…Van Lingen et al (69) followed 178 patients with no significant coronary stenosis (Ͻ50%) by CTA for 1 year (range 51 to 1,113 days) and found no unstable angina, MI, or death, although 2 patients did have coronary revascularization. MRI.…”