Prognostic Cut Point for Breast Cancer Age of Diagnosis

Hajizadeh, Ebrahim; Abdollahi, Mahbubeh; Baghestani, Ahmad Reza; Haghighat, Setareh

doi:10.5812/ijcm.9291

Cited by 2 publications

(2 citation statements)

References 21 publications

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“…5 Kesintasan 5 tahun pasien kanker payudara usia <50 tahun sebesar 55-80%, sedangkan usia 50 tahun sebesar 70-85%. 6 Kanker payudara tipe epitelial/karsinoma payudara adalah keganasan pada jaringan payudara yang dapat berasal dari epitel duktus dan lobulus. Menurut WHO Classification of Tumours of the Breast, karsinoma payudara dikelompokkan menjadi dua kategori utama yaitu karsinoma invasif NST dan special subtypes.…”

Section: Pendahuluanunclassified

Histomorphological and Demographic Profile of Breast Carcinoma in Anatomical Pathology Department FKUI/RSCM 2016-2019

Wongkar¹,

Hellyanti²,

Hayati³

2022

MPI

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BackgroundInvasive breast carcinoma (IBC) is the most commonly diagnosed cancer in woman in the world and Indonesia. IBC is classified into two main categories: IBC of no special type (NST) and special types. This retrospective study aims to provide histomorphological profile of mastectomy cases of IBC in Anatomical Pathology Department, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital (PA FKUI/RSCM) 2016-2019.MethodsThis is a descriptive research with cross-sectional design of mastectomy cases, using secondary data from the archives of PA FKUI/RSCM, starting from 2016- 2019. Collecting clinical data as well as observing several histopathologic parameters including histological type, grade, atypical mitotic features, lymphovascular invasion, and lymph node metastases. Tumour classification was made based on the WHO breast criteria in 2019.ResultsDuring the 2016-2019 period there were 144 cases of IBC. 99.3% of cases occurred in female patients, mostly in the age group from 40 to 59 years and unilateral. The majority had tumour sizes ranging >2-5 cm and were stage II. About a third of cases had received neoadjuvant chemotherapy, most commonly in advanced local stage tumors. Most histologic type (65.3%) were IBC of NST and 52.8% of cases were grade 2. There were 92 (63.4%) cases with atypical mitotic features, most commonly found in stage III. Lymphovascular invasion was found in 38.9% of cases and lymph node metastasis was found in 63.2% of cases.ConclusionIBC is the most common cancer in woman, with the most common histologic type were IBC, grade 2, stage II or more. Most of the cases show atypical mitosis, which is most commonly found in stage III. The findings of lymphovascular invasion did not always coincide with the findings of lymph node metastases.

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Section: Pendahuluanunclassified

Histomorphological and Demographic Profile of Breast Carcinoma in Anatomical Pathology Department FKUI/RSCM 2016-2019

Wongkar¹,

Hellyanti²,

Hayati³

2022

MPI

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“…Generally, the younger the age below menopause are the more aggressive of the cancer. [10][11][12] A recent article of American Society of Clinical Oncology states that the overall 5-year survival rate of breast cancer patients in the United States, is from 75% to 89%. As a result of improved treatment and earlier detection, mortality from breast cancer has begun to decrease substantially.…”

Section: Introductionmentioning

confidence: 99%

Serum ferritin, lactate dehydrogenase, and gamma glutamyl transferase levels in patients with breast carcinoma

S¹,

Deepak²,

Mahmood³

2021

IJCBR

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Cancer also known as malignant neoplasm, is a broad group of various diseases. In cancer, cells divide and grow uncontrollably, forming malignant tumours, and invade nearby parts of the body. There are over 200 different known cancers that afflict humans. Malignant neoplastic lesions are the eighth leading cause accounting for 6.7% of the total medically certified deaths in India. Breast cancer is by far the most frequent cancer among women with an estimated 2.58 million new cancer cases diagnosed in 2019 (23% of all cancers), and ranks second overall (10.9% of all cancers). It is now the most common cancer both in developed and developing regions with around 690000 new cases estimated in each region (population ratio1:4). Breast cancer is the Most Common cancer in all urban areas in India, and 2nd most common in the rural areas. The most recent data Population Based Cancer Registry PBCR 2016 -2018 tells us that breast cancer accounts for 25% to 31% of all cancers in women in cities (Mumbai, Delhi, Chennai, Ahmedabad, Bengaluru, Bhopal etc.). Breast cancer alone accounts for around 14% of total female neoplasm deaths.

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Prognostic Cut Point for Breast Cancer Age of Diagnosis

Cited by 2 publications

References 21 publications

Histomorphological and Demographic Profile of Breast Carcinoma in Anatomical Pathology Department FKUI/RSCM 2016-2019

Histomorphological and Demographic Profile of Breast Carcinoma in Anatomical Pathology Department FKUI/RSCM 2016-2019

Serum ferritin, lactate dehydrogenase, and gamma glutamyl transferase levels in patients with breast carcinoma

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