Prognostic factors affecting survival of patients with intertrochanteric femoral fractures over 90 years treated with proximal femoral nailing

Ergin, Ömer; Bayram, Serkan; Anarat, Fikret Berkan; Yağcı, Taha Furkan; Balcı, Halil İbrahim

doi:10.1007/s00068-020-01355-8

Cited by 8 publications

(9 citation statements)

References 25 publications

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“…Before the pandemic, however, NLR was neither a consistent predictor of 30-day readmissions 21–23 nor 1-year mortality in other populations 24,25 . Studies that have found associations between NLR and 30-day readmission had higher NLR scores than the upper tertile group of our study 24 . In addition, admission NLR scores may not be associated with LOS, 30-day readmission, and postdischarge mortality unless the ratio is very large because the decrease in lymphocytes is a late phenomenon during admission 26,27 .…”

Section: Discussioncontrasting

confidence: 75%

“…In terms of 30-day readmissions and 6-month and 1-year mortality, there were no studies of hospitalized COVID-19 patients to compare with ours. Before the pandemic, however, NLR was neither a consistent predictor of 30-day readmissions 21–23 nor 1-year mortality in other populations 24,25 . Studies that have found associations between NLR and 30-day readmission had higher NLR scores than the upper tertile group of our study 24 .…”

Section: Discussioncontrasting

confidence: 68%

“…24,25 Studies that have found associations between NLR and 30-day readmission had higher NLR scores than the upper tertile group of our study. 24 In addition, admission NLR scores may not be associated with LOS, 30-day readmission, and postdischarge mortality unless the ratio is very large because the decrease in lymphocytes is a late phenomenon during admission. 26,27 Measuring NLR later in the hospitalization can better predict the LOS and 30-day mortality.…”

Section: Discussionmentioning

confidence: 46%

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Association between the Neutrophil-to-Lymphocyte Ratio and Inpatient Mortality in Hospitalized Older Veterans with COVID-19 Infection

Gonnell,

Resendes,

Quinones

et al. 2023

Southern Medical Journal

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Because older adults have suffered disproportionally serious coronavirus disease 2019–related clinical complications, identifying hospitalized older individuals at risk for poor outcomes with a tool like the neutrophil-to-lymphocyte ratio, an indicator of systemic inflammation, may help determine prognosis. We studied the ability of the neutrophil-to-lymphocyte ratio to predict in-hospital mortality and other outcomes of veterans with coronavirus disease 2019 infection admitted to Veterans Affairs hospitals in Florida from March 1 to August 31, 2020.

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Section: Discussioncontrasting

confidence: 75%

Section: Discussioncontrasting

confidence: 68%

Section: Discussionmentioning

confidence: 46%

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Association between the Neutrophil-to-Lymphocyte Ratio and Inpatient Mortality in Hospitalized Older Veterans with COVID-19 Infection

Gonnell,

Resendes,

Quinones

et al. 2023

Southern Medical Journal

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“…Elevated NLR appeared to predict more severe tibial plateau fractures [ 23 ]. In patients with intertrochanteric fractures older than 90 years treated with proximal femoral nailing, WBC, NLR, and PLR values were also elevated but were not significantly correlated with survival [ 24 ]. Early postoperative NLR may help to recognize postoperative delirium in elderly patients undergoing surgery for lower limb fracture under nongeneral anaesthesia [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Value of the Blood Neutrophil-to-Lymphocyte Ratio and Monocyte-to-Lymphocyte Ratio in Tibia Fracture-Related Infection

et al. 2022

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Objective. The diagnostic value of neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR) in predicting fracture-related infection (FRI) in tibia fracture patients remains to be explored. Methods. A retrospective controlled study was carried out with 170 tibia FRI patients and 162 control subjects. The following information was evaluated at admission: age, gender, clinical features, number of white blood cells (WBCs), neutrophils, lymphocytes, monocytes, red blood cells (RBCs), platelets, level of hemoglobin, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR), as well as NLR, MLR, and PLR. Results. The number of lymphocytes, RBCs, and platelets in the FRI group was higher than those in the control group, while the number of neutrophils and ESR level was lower ( P < 0.05 ). The level of NLR and MLR was significantly lower in patients with tibia FRI than in control subjects ( P < 0.05 ). Both indicators were positively correlated with WBCs, CRP level, and ESR level ( P < 0.001 ). The results of logistic regression analysis showed that five variables including NLR, MLR, platelets, fracture pattern (closed or open fracture), and site pattern (single or multiple site) were used to construct the FRI risk predictor. The ROC curve analysis result showed that FRI risk predictor yielded the highest AUC, with a sensitivity of 91.2% and a specificity of 90.1%, and made the distinction efficiently between tibia FRI patients and non-FRI patients. Conclusion. NLR and MLR were decreased in tibia FRI patients compared to non-FRI patients. Both indicators had a positive correlation with WBCs, CRP level, and ESR level. FRI risk predictor constructed based on five variables including NLR and MLR had a high diagnostic value for tibia FRI.

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“…Growing literature describes the usefulness of the NLR in assessing the postoperative outcome in orthopaedic surgery. [1][2][3][4][5] Trochanteric region fractures are extracapsular fractures of the proximal femur occurring between the greater and lesser trochanter. They are more common in the elderly due to the osteoporotic process and the increased risk of falls, but can occur also in the young, resulting from high-energy traumatisms.…”

mentioning

confidence: 99%

NLR as a Prognostic Tool in Orthopaedic Surgery in Elderly Extra-Articular Hip Fracture: A Significant Increase in NLR 24 Hours after Surgical Intervention

Tomaino

Pansieri

Vigna

et al. 2022

The Journal of Hip Surgery

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Neutrophil-to-lymphocyte ratio (NLR) was developed as a diagnostic and prognostic tool in many medical conditions, and its use is spreading as a predictor of postoperative outcome in orthopaedic surgery. The aim of this study is to investigate the improvement of NLR 24 hours after surgical intervention in a cohort of 91 patients (F/M = 68/23) with hip fracture who underwent femur intramedullary fixation. Patients were 84.7 ± 7.9 years old, and the mean hospital stay was 13.4 ± 4.7 days, with a mean delay to surgery of 1.9 ± 1.4 days. A significant increase in NLR between baseline (T0) and 24 hours after surgical intervention (T1) was observed in the study sample overall and on subgroup analysis by gender. Nevertheless, no significant effect of NLR on the length of hospital stay was observed.

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Prognostic factors affecting survival of patients with intertrochanteric femoral fractures over 90 years treated with proximal femoral nailing

Cited by 8 publications

References 25 publications

Association between the Neutrophil-to-Lymphocyte Ratio and Inpatient Mortality in Hospitalized Older Veterans with COVID-19 Infection

Association between the Neutrophil-to-Lymphocyte Ratio and Inpatient Mortality in Hospitalized Older Veterans with COVID-19 Infection

Diagnostic Value of the Blood Neutrophil-to-Lymphocyte Ratio and Monocyte-to-Lymphocyte Ratio in Tibia Fracture-Related Infection

NLR as a Prognostic Tool in Orthopaedic Surgery in Elderly Extra-Articular Hip Fracture: A Significant Increase in NLR 24 Hours after Surgical Intervention

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