Prognostic Factors In Epithelial Ovarian Carcinoma: A Reference Institution Experience

Abstract

SUMMARY Aim

Prognostic Factors Affecting Survival in Patients with Ovarian Cancer: A 5-Year Experience in an University Hospital.

“…4,5 In our study abdominal distension was seen in 44.6% of patients, which was followed by abdominal/pelvic pain with a rate of 19.6%, and vaginal bleeding/irregular menstrual cycles was found in 35.7%. In accordance with our study Oge et al 7 also reported abdominal swelling as the most common complaint (59.1%), and the second most frequent complaint was reported as abdominal pain Cancer statistics often use 5-year OS rate to present a better idea of the longer-term outlook for people with cancer. 5 We found that the OS for OC was 94.3%, 66.4%, and 42.8% at 1, 3, and 5 years, respectively.…”

“…Some studies reported that increasing age was most strongly associated with poor survival. 9,10,[18][19][20]22 However, in the other studies of Oge et al 7 and Buldanlı et al 11 revealed that age was not was not effected by the age of the patients in OC.…”

“…In a study performed in Turkey, according to the surgical stages I, II, III and IV median survival was 78.5 months, 60.1 months, 33.9 months and 16.1 months respectively and significantly different. 7 In a study by Karaca 21 study, a number of 13.590 women (from 9 nationwide cancer registry centers) were evaluated who got gynecological cancer diagnosis (31.2% OC) in Turkey between 2004 and 2011, overall 5-year observed OC survival rate was 46%. Buldanlı et al reported that OS was 51.6% in Western Turkey.…”

“…4,5 In the literature, survival depends on many factors such as patient's family history, multiple comorbidities, postoperative complications, chemotherapy toxicities, increasing age, postmenopausal period, recurrence, presence of positive lymph nodes, advanced stage and grade, carcinosarcomas subtype, ascites, never having been pregnant and having never taken oral contraceptives, as well as lifestyle factors such as performance status, smoking and obesity. [6][7][8][9][10][11] Statistics show that survival from all cancers in women was 64.2% while it was approximately 45.0% for OC globally and the 5-year survival rate has improved in OC by only 9% since 1975 even in high-income countries.…”

<p>Parity as a Prognostic Factor in Patients with Advanced-Stage Epithelial Ovarian Cancer</p>

“…Current results demonstrated that the median (95% CI) follow-up survival time for surviving ASEOC patients was 22 (18)(19)(20)(21)(22)(23)(24)(25) months. This means that, in general, fifty percent of the ASEOC patients survived at least 22 months.…”