2017
DOI: 10.17235/reed.2017.4517/2016
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Prognostic factors of liver cirrhosis mortality after a first episode of spontaneous bacterial peritonitis. A multicenter study

Abstract: Short- and long-term mortality of spontaneous bacterial peritonitis is still high. The main prognostic factors for mortality are impairment of liver and kidney function. MELD and the Charlson index are good markers of survival.

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Cited by 5 publications
(12 citation statements)
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“…It is estimated to represent around 25% to 31% of all infections in these patients and a prevalence ranging from 10% to 30% in inpatient cirrhotic cohorts with ascites [ 5 ]. The occurrence of first episode of SBP is considered an inflection point in the natural history of cirrhosis and ascites, denoting further decompensation and profound impact on survival (even after resolution of SBP) [ 3 ]. The 30-day in-hospital mortality of SBP is variable but has been reported to be anywhere between 18% [ 17 ] and up to 31.9% [ 16 ].…”
Section: Discussionmentioning
confidence: 99%
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“…It is estimated to represent around 25% to 31% of all infections in these patients and a prevalence ranging from 10% to 30% in inpatient cirrhotic cohorts with ascites [ 5 ]. The occurrence of first episode of SBP is considered an inflection point in the natural history of cirrhosis and ascites, denoting further decompensation and profound impact on survival (even after resolution of SBP) [ 3 ]. The 30-day in-hospital mortality of SBP is variable but has been reported to be anywhere between 18% [ 17 ] and up to 31.9% [ 16 ].…”
Section: Discussionmentioning
confidence: 99%
“…Development of hepatic encephalopathy and septic shock were also associated with increased short-term mortality in our study. Impairment of liver function, as suggested by the MELD score, was reported as a good predictor of mortality in SBP in several studies throughout the literature [ 3 ]. Several MELD values, such as 16.5 [ 3 ], 20.5 [ 21 ], and 22 [ 22 ], have been suggested as optimal cut-off points for predicting a worse prognosis in these cohorts of patients.…”
Section: Discussionmentioning
confidence: 99%
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“…Παράγοντες κινδύνου είναι η βαρύτητα της ηπατικής νόσου και η κίρρωση αιθυλικής αλκοόλης [121]. Ο συχνότερα ταυτοποιούμενος μύκητας είναι η Αναφορικά με τους παράγοντες κινδύνου ενδονοσοκομειακής θνητότητας, πέραν όσων αναφέρθηκαν για τις λοιμώξεις γενικά, στις μελέτες της ΑΒΠ αναφέρονται συγκεκριμένα δείκτες βαρύτητας της ηπατικής νόσου όπως η υψηλή τιμή INR[122],το υψηλό MELD score στην εισαγωγή, η παρουσία ηπατοκυτταρικού καρκίνου[123], η ύπαρξη ηπατικής εγκεφαλοπάθειας και η νεφρική δυσλειτουργία [124]. Καθυστέρηση στη διάγνωση άνω των 12 ωρών, οδηγεί σε 2.7 φορές πιο αυξημένη θνητότητα[125] ενώ οι λοιμώξεις από MDR συσχετίζονται με 4 φορές υψηλότερο κίνδυνο θανάτου [7].…”
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