Prognostic role of pre-treatment magnetic resonance imaging (MRI)-based radiomic analysis in effectively cured head and neck squamous cell carcinoma (HNSCC) patients

Alfieri, Salvatore; Romanò, Rebecca; Bologna, Marco; Calareso, Giuseppina; Corino, Valentina D. A.; Mirabile, Aurora; Ferri, Andrea; Bellanti, L; Poli, Tito; Marcantoni, Alessandra; Grosso, E; Tarsitano, Achille; Battaglia, Salvatore; Blengio, F.; Martino, Iolanda De; Valerini, Sara; Vecchio, Stefania; Richetti, A.; Deantonio, Letizia; Martucci, Francesco; Grammatica, Alberto; Ravanelli, Marco; Ibrahim, Toni; Locati, Laura D.; Orlandi, Ester; Bossi, Paolo; Mainardi, Luca; Licitra, Lisa

doi:10.1080/0284186x.2021.1924401

Cited by 17 publications

(12 citation statements)

References 43 publications

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“…The feature variability detected by radiomics in patients with residual myomas may be an early indicator of continued myoma progression, enabling the identification of heterogeneity characteristics, i.e. the radiomics features that identify heterogeneous changes in myomas, at the microscopic level 23 , 24 . Furthermore, quantitative measurements of specific tissue areas can provide additional information on subtle differences in tissue structure, including areas of necrosis, cell proliferation and neoangiogenesis 25 , 26 , that relate to intrinsic regrowth mechanisms of residual myomas not visible to the naked eye.…”

Section: Discussionmentioning

confidence: 99%

Prediction using T2‐weighted magnetic resonance imaging‐based radiomics of residual uterine myoma regrowth after high‐intensity focused ultrasound ablation

Zhou

Zhang

Chen

et al. 2022

Ultrasound in Obstet & Gyne

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What are the novel findings of this work? T2-weighted magnetic resonance imaging (T2WI)-based radiomics parameters can predict regrowth of residual uterine myomas within 1 year after high-intensity focused ultrasound (HIFU) treatment. What are the clinical implications of this work?Accurate prediction of residual myoma regrowth is critical for the early customization of chronic disease management plans after HIFU ablation in patients with uterine myomas. T2WI-based radiomics may have a role in this regard.

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Section: Discussionmentioning

confidence: 99%

Prediction using T2‐weighted magnetic resonance imaging‐based radiomics of residual uterine myoma regrowth after high‐intensity focused ultrasound ablation

Zhou

Zhang

Chen

et al. 2022

Ultrasound in Obstet & Gyne

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“…Recently, with the rapid development of sequencing technology, gene mutations related to OTSCC and genetic biomarker candidates related to poor prognosis have been reported 29–31 . In addition, with the development of radiomics and machine learning techniques, radiomics signatures related to the prognosis of head and neck cancer have been developed, and prognostic prediction models have been reported 32–34 . Through additional research on these genetic or radiomics biomarkers, the development of a predictive model that can more precisely predict the disease risk of pT1‐2N0 early stage OTSCC patients and select high‐risk patients in need of active treatment is necessary.…”

Section: Discussionmentioning

confidence: 99%

Long‐term outcomes of early stage oral tongue cancer: Main cause of treatment failure and second primary malignancy

Park

Lim

Koh

et al. 2022

Laryngoscope Investig Oto

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Objective: We attempted to investigate the long-term outcomes, prognostic factors, treatment failures, second primary malignancies, and salvage therapies in early (pT1-2N0) oral tongue squamous cell carcinoma (OTSCC). Methods:We retrospectively analyzed the medical records of 295 early stage OTSCC patients.Results: Two hundred ninety-five patients were enrolled. The average follow-up period was 64.5 months (range, 1-190 months). Five-year recurrence-free survival rate was 84.8% and disease-specific survival rate was 91.2%. On multivariate analysis, only the depth of invasion (DOI) exhibited significant correlations with the disease recurrence. Patient's age and DOI demonstrated a significant association with survival. A total of 53 recurrence and 35 death events occurred, with the main cause of treatment failure being regional or local recurrence. In recurrent cases, the success rate of salvage treatment was 42% at 5 years. During the follow-up period, second primary malignancy occurred in 13 patients, and 8 (61.5%) of those patients were successfully treated.Conclusions: In pT1-2N0 OTSCC, regional or local recurrence is the main recurrence pattern, whereas age and DOI >5 mm are significant prognostic factors related to recurrence and survival. Since several patients experienced second primary malignancies in the head and neck, careful and thorough surveillance may be required to detect second primary lesions.

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“…Several previously published studies have also reported the predictive value of intratumoral heterogeneity for patients irradiated for the first time for HNC. In a study involving pre-irradiation MRI, Alfieri et al found a signature associated with the patients outcomes that included three radiomics features correlated with tumor heterogeneity [35]. Akram et al also performed a radiomics study in 14 patients irradiated with IMRT for nasopharyngeal carcinoma.…”

Section: Discussionmentioning

confidence: 99%

[18F]-FDG PET and MRI radiomic signatures to predict the risk and the location of tumor recurrence after re-irradiation in head and neck cancer

Beddok

Orlhac

Calugaru

et al. 2022

Eur J Nucl Med Mol Imaging

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HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

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Prognostic role of pre-treatment magnetic resonance imaging (MRI)-based radiomic analysis in effectively cured head and neck squamous cell carcinoma (HNSCC) patients

Cited by 17 publications

References 43 publications

Prediction using T2‐weighted magnetic resonance imaging‐based radiomics of residual uterine myoma regrowth after high‐intensity focused ultrasound ablation

Prediction using T2‐weighted magnetic resonance imaging‐based radiomics of residual uterine myoma regrowth after high‐intensity focused ultrasound ablation

Long‐term outcomes of early stage oral tongue cancer: Main cause of treatment failure and second primary malignancy

[18F]-FDG PET and MRI radiomic signatures to predict the risk and the location of tumor recurrence after re-irradiation in head and neck cancer

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