2007
DOI: 10.1016/j.healun.2007.07.023
|View full text |Cite
|
Sign up to set email alerts
|

Prognostic Value of Brain Natriuretic Peptide in Heart Transplant Patients

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
21
0
1

Year Published

2008
2008
2021
2021

Publication Types

Select...
6
1
1

Relationship

0
8

Authors

Journals

citations
Cited by 23 publications
(22 citation statements)
references
References 37 publications
0
21
0
1
Order By: Relevance
“…Their study is key for explaining how, even in the context of clinical stability, a sustained elevation of BNP levels could be due to the presence of a persistent sub-clinical inflammatory response in the graft, with the consequent deleterious effects on graft function in the medium-long term. In a previous study by our group, 21 we observed the prognostic value of BNP in heart transplant patients. In the context of clinical and hemodynamic stability, and excluding possible confounding factors, significantly higher mean BNP levels were found in four serial determinations over the first year post-HT in the group of patients who developed events (death, late rejection or ventricular dysfunction) during follow-up (145 Ϯ 50 vs 92 Ϯ 92 pg/ml; p ϭ 0.01).…”
Section: Discussionmentioning
confidence: 80%
See 2 more Smart Citations
“…Their study is key for explaining how, even in the context of clinical stability, a sustained elevation of BNP levels could be due to the presence of a persistent sub-clinical inflammatory response in the graft, with the consequent deleterious effects on graft function in the medium-long term. In a previous study by our group, 21 we observed the prognostic value of BNP in heart transplant patients. In the context of clinical and hemodynamic stability, and excluding possible confounding factors, significantly higher mean BNP levels were found in four serial determinations over the first year post-HT in the group of patients who developed events (death, late rejection or ventricular dysfunction) during follow-up (145 Ϯ 50 vs 92 Ϯ 92 pg/ml; p ϭ 0.01).…”
Section: Discussionmentioning
confidence: 80%
“…Furthermore, elevation of these levels (BNP or N-terminal proBNP) also appears to have prognostic value with regard to the development of late graft dysfunction or death. 19,21,24,25 Most of these studies have the limitations of including few patients, being based on a single laboratory determination, or not excluding patients who may have had an elevated BNP level for other reasons.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In humans with heart disease, clinical symptoms and LV function were improved after treatment with a betablocker and angiotensin converting-enzyme inhibitor; this treatment also resulted in a significant decrease in the levels of ANP and BNP [12,13,15]. Similarly, event-free survival in patients undergoing heart transplantation was better in patients with a decreased BNP than in patients with an increased BNP [19,20]. In 3 dogs with PDA, LVID d and FS decreased after operation concomitant with a decrease in the plasma ANP and BNP concentrations [2].…”
Section: Discussionmentioning
confidence: 99%
“…In all four HF stages and in heart transplant recipients [ 39 ], plasma BNP or NT-proBNP provides prognostic information. In a substudy of the Val-HeFT trial, those with plasma BNP concentration in the highest quartile at baseline had a signifi cantly greater mortality at 2 years than those with a plasma BNP in the lowest quartile (32.4% vs 9.7%) [ 40 ].…”
Section: Prognostic Marker In Hfmentioning
confidence: 99%