Prognostic value of cervical size and pelvic lymph node status assessed by computed tomography for patients with uterine cervical cancer treated by radical radiation therapy

Bax and Bcl-2 expressions predict response to radiotherapy in human cervical cancer

“…Radiotherapy is the most important non-surgical treatment for cervical carcinoma. Several potential markers of response to radiotherapy in cervical carcinoma, such as stage and bulk, histological type and grade, the presence of lymphovascular invasion, and lymph node status, have been identi®ed (Toita et al 1995). The tumor stage is still believed to be the most important determinant of prognosis, and tumor size has also been used as a marker of prognosis for many years (Virostek et al 1996).…”

Interindividual Variability of Lymph Drainages in Patients with Cervical Cancer

“…Many authors have demonstrated the correlation between recurrences in cervical cancer and primary tumor size, lymph node involvement, resection margins and depth of stromal invasion [1,9,31,33,36]. Gadducci et al [9] reported on more than 150 patients after hysterectomy and postoperative irradiation: < 1% of all 117 lymph node-negative patients developed locoregional recurrences, but > 50% of all patients with three or more metastatically involved pelvic lymph nodes relapsed after surgery and postoperative irradiation.…”

Computed tomography analysis of causes of local failure in radiotherapy for cervical carcinoma

“…Investigators 29,31,32,33 have indicated recently that the tumor size, as assessed by CT images, also affects the prognosis of patients who were treated by radiotherapy. Our analysis of the cervical area during intracavitary therapy demonstrated that the area in the local control group was significantly smaller than that in the local failure group, and the local control rate decreased with the increasing the cervical area, especially over 18 cm 2 .…”