Prognostic value of extensive coronary calcium quantities in symptomatic males?a 5-year follow-up study

Abstract

Symptomatic males with extensive CSs carry an even higher risk for future events than other symptomatic males with advanced CAD. In these patients, EBT-based calcified plaque burden and angiographic indices of disease severity may have a complementary role in predicting future cardiovascular events.

Non-Invasive Computed Tomographic Coronary Angiography for Patients with Suspected Coronary Artery Disease

“…Slight difference in results may be due to difference in size of study population. Arad Y et al (2005) [7] and Mohlenkamp et al [8] in their studies observed that coronary calcification was a strong and independent predictor of CAD in all age groups and the risk of CAD increased with the increasing calcium score. It was also found to predict the risk of CAD events independenly of standard risk factors.…”

Comparison of dual-source and electron-beam CT for the assessment of coronary artery calcium scoring

“…The difference log(DSCT+1)-log(EBCT+1) was significantly negative by paired t-test for each replicate (1,2), and for the mean of replicates (3) We additionally performed ordinary linear regression (OLR) of log(DSCT+1) on log(EBCT+1) for each reader and the pooled data (1, 2, 3). While the intercept was always compatible with zero, the slope was 0.938 (0.…”

“…On the Agatston score scale, a correction factor from DSCT to EBCT based on the mean of replicates (3) from PBR would read: log(DSCT+1)5log(EBCT+1)60.975: EBCT5(DSCT+1) 1.026 -1. Consecutively, we applied the correction factor to the DSCT scores.…”

“…Results: EBCT scores were on average slightly higher than DSCT scores (281¡569 vs 241¡502; p,0.05). In regression analysis R Cardiac CT allows the detection and quantification of coronary artery calcification (CAC) and may thus add important in vivo information on the path from risk factor exposure to formation of clinical events [1][2][3][4]. Because of its advantages of being a fast technique with limited radiation exposure to the patients, various published clinical outcome data from CAC are based on electronbeam CT (EBCT), and therefore cut-points have been established for EBCT scans.…”

Coronary CT Angiography as an Alternative to Invasive Coronary Angiography

“…There is a linear relationship between the amount of coronary calcium and coronary atherosclerosis, that is, the more coronary calcium the higher the likelihood of coronary stenosis (Rumberger et al 1995), and proportionally prognostic -the higher the calcium score the greater the likelihood of coronary events (O'Rourke et al 2000). Moehlenkamp and colleagues recently demonstrated that coronary calcium scoring not only adds prognostic value to the Framingham risk model, but also that it's value is greater than hsCRP (Mohlenkamp et al 2003). Also the recent randomized Eisner Trial demonstrated that coronary calcium testing leads to better downstream control of coronary risk factors (Rozanski et al 2011).…”