2020
DOI: 10.1097/mnm.0000000000001337
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Prognostic value of imaging markers from 18FDG-PET/CT in paediatric patients with Hodgkin lymphoma

Abstract: Objective Identification of imaging prognostic parameters for early therapy personalisation to reduce treatment-related morbidity in paediatric Hodgkin lymphoma (HL). Our aim was to evaluate quantitative markers from baseline 2-[18F]fluoro-2-deoxy-d-glucose PET/CT as prognostic factors for treatment outcomes. Another goal was assessing the prognostic value of Deauville score at interim PET/CT. Methods Twenty-one patients were prospectively enrolled. Med… Show more

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Cited by 8 publications
(5 citation statements)
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“…High “asphericity”, a textural parameter reflecting the lesion surface complexity was also correlated with the interim PET inadequate response. In a most recent prospective study in a small population of HL pediatric patients [ 152 ], four textural parameters, from the textural families of the grey-level co-occurrence matrix and neighborhood grey tone difference matrix were also predictors of interim PET treatment response ( Table 2 ).…”
Section: Pediatric Lymphomasmentioning
confidence: 99%
“…High “asphericity”, a textural parameter reflecting the lesion surface complexity was also correlated with the interim PET inadequate response. In a most recent prospective study in a small population of HL pediatric patients [ 152 ], four textural parameters, from the textural families of the grey-level co-occurrence matrix and neighborhood grey tone difference matrix were also predictors of interim PET treatment response ( Table 2 ).…”
Section: Pediatric Lymphomasmentioning
confidence: 99%
“…The CUDIM participated in local research projects to reduce treatment-related morbidity in pediatric HL identifying four textural features in the bPET as candidates for predicting early response to chemotherapy at iPET (3). Analyses were used for optimal cut-off values to separate responders at iPET according to the Dauville score.…”
Section: Pet/ct In Lymphoma Staging and Restaging In Uruguaymentioning
confidence: 99%
“…Radiomics, an emerging field of research aiming to extract mineable, quantitative, high-dimensional data from clinical images, has been suggested as a solution [ 12 , 13 , 14 ]. Various studies have explored the possibilities offered by radiomics in HL [ 15 ] whether for computer-aided histological classification [ 16 ], staging [ 17 , 18 ], early metabolic response assessment [ 19 , 20 , 21 ], or refractory disease prediction [ 22 , 23 ].…”
Section: Introductionmentioning
confidence: 99%