Prognostic value of the Quick Sepsis-related Organ Failure Assessment (qSOFA) score among critically ill medical and surgical patients with suspected infection in a resourcelimited setting

Bischop, L A; Wilson, Douglas P.; Wise, Robert; Savarimuthu, Sugeevan; Anesi, George L

doi:10.7196/ajtccm.2021.v27i4.158

Cited by 5 publications

(4 citation statements)

References 27 publications

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“…They concluded that this score is very useful in resource-limited intensive care settings in predicting mortality among critically ill medical or surgical patients having sepsis. 17 We had similar results, and a score of greater than two was associated with increased mortality in our study participants.…”

Section: Discussionsupporting

confidence: 80%

Increase Mortality Rate in Sepsis Patients with qSOFA Score Greater than Two

Khan

Mahmood

Qayyum

et al. 2022

PAFMJ

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Objective: To look for patients of sepsis with a qSOFA score of more than two and an association of a high qSOFA score with mortality and other socio-demographic factors. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Medicine, Combined Military Hospital, Sialkot Pakistan, from Nov 2021 to May 2022. Methodology: All baseline and relevant investigations were carried out at the time of initial clinical assessment, and the qSOFA score was calculated by a consultant medical specialist for all the patients diagnosed with the septic condition. Patients were followed up for two weeks to look for mortality. Results: A total of 500 patients, managed for sepsis during the study period were included in the study. Of them, 298(59.6) were males, while 202(40.4) were females. Out of all the patients in the study, 379(75.8) had a qSOFA score of two or less than two, while 121(24.2) had a qSOFA score of more than two. Increased mortality, patients with more than 50 years and comorbid illnesses were found statistically significantly more in the group having a qSOFA score of more than two (p-value<0.001). Conclusion: Mortality was significantly high in patients with sepsis who had a qSOFA score greater than two at the time of initial assessment compared to those with a score of two or less.

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Section: Discussionsupporting

confidence: 80%

Increase Mortality Rate in Sepsis Patients with qSOFA Score Greater than Two

Khan

Mahmood

Qayyum

et al. 2022

PAFMJ

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“…Likewise, the prognostic value of the qSOFA scale was very noteworthy in our results, detecting a higher mortality in patients who, at the time of PSC activation, exhibited the three positive factors of the scale. Its ease of implementation makes it a useful tool in an era of limited resources [51]. Very interesting studies have been published regarding the use of automatic alerts for the detection of sepsis, and the use of artificial intelligence, big data, and machine learning in this context, which, although in the preliminary phases for clinical use, are tools that should be kept in mind for use in the near future [52].…”

Section: Discussionmentioning

confidence: 99%

Decrease in Mortality after the Implementation of a Hospital Model to Improve Performance in Sepsis Care: Princess Sepsis Code

Méndez,

Figuerola,

Ramasco

et al. 2024

JPM

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Sepsis is a time-dependent disease whose prognosis is influenced by early diagnosis and therapeutic measures. Mortality from sepsis remains high, and for this reason, the guidelines of the Surviving Sepsis Campaign recommend establishing specific care programs aimed at patients with sepsis. We present the results of the application of a hospital model to improve performance in sepsis care, called Princess Sepsis Code, with the aim of reducing mortality. A retrospective study was conducted using clinical, epidemiological, and outcome variables in patients diagnosed with sepsis from 2015 to 2022. A total of 2676 patients were included, 32% of whom required admission to the intensive care unit, with the most frequent focus of the sepsis being abdominal. Mortality in 2015, at the beginning of the sepsis code program, was 24%, with a declining rate noted over the study period, with mortality reaching 17% in 2022. In the multivariate analysis, age > 70 years, respiratory rate > 22 rpm, deterioration in the level of consciousness, serum lactate > 2 mmol/L, creatinine > 1.6 mg/dL, and the focus of the sepsis were identified as variables independently related to mortality. The implementation of the Princess Sepsis Code care model reduces the mortality of patients exhibiting sepsis and septic shock.

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“…In this issue of the AJTCCM, Bishop et al [18] retrospectively evaluated the role of a positive qSOFA score in predicting mortality in medical and surgical patients with suspected infection from the database of a regional hospital's critical care unit comprising of high care (HC) and ICU patients. The predictive ability of qSOFA for all patients in their database, including those without infections, has been previously reported.…”

mentioning

confidence: 99%

“…The predictive ability of qSOFA for all patients in their database, including those without infections, has been previously reported. [18,19] This cohort of 1 162 patients consists predominantly of surgical patients (60%) who were mechanically ventilated. This is a useful study, and the authors ought to be congratulated for their efforts, considering the paucity of qSOFA data in ICU settings, the need for data from poorly resourced regions and the global lack of qSOFA data for surgical cohorts in particular.…”

mentioning

confidence: 99%