Tetanus is an infectious and non-contagious disease capable of causing a state of hyperexcitability in the central nervous system. In order to prevent the development of the infection, the tetanus vaccine was implemented. However, for effective protection, a complete and adequate immunization is necessary. The aim of the study was to identify the factors that can interfere with the tetanus vaccination scheme in the elderly population. This is an integrative, retrospective, descriptive-exploratory literature review with a qualitative approach, carried out through the Portal de Periódicos CAPES. After the search, 2,313 studies were found, of which 18 were eligible for the final sample. Factors that negatively affect tetanus vaccine coverage in the elderly population were identified as the number of incomplete doses and the absence of tetanus booster; absence of vaccination campaigns and socioeconomic and demographic aspects. Therefore, it was determined that tetanus is a disease that can cause serious complications and concerns to health systems, with the elderly being the population most affected by the infection, both due to changes in their physiology and the decrease in the levels of protective antibodies.