Progress in the Synthesis of Aroyl Compounds

Abstract

Aroyl compounds exhibit various biological activities and are important fine chemicals as well. Therefore, their synthetic methods have attracted considerable attention. It is the first time to summarize the synthetic methods of aroyl compounds in the past five to eight years. These reactions can be classified into three parts by their reaction mechanism, namely, coupling reaction catalyzed transition metals, the free radical mechanism and aromylation reactions carried out by other mechanisms. It is expected that inspiration of new synthetic methods will be provided for the synthesis of compounds bear aroyl group in this review.

Direct α-methylenation of triazines to terminal olefins with DMA

“…12 Our group has been engaged in the construction, derivatization, and activity evaluation of triazine derivatives for years. 13 We recently demonstrated the copper-catalysed oxidation of arylmethyl triazines to aroyl triazines in DMA with water (Scheme 1), and we proved that H 2 O is vital for the oxidation transformation. 13 a During the optimization process, unexpectedly the terminal olefin 2a was produced in 36% yield when K 2 S 2 O 8 was added to the reaction (Table 1, entry 1).…”

HPLC analysis of 16 compounds from Artemisia ordosica

“…Compounds 1 , 2 and 5 belonged to phenylpropanoids, compounds 8 , 9 and 12 were somewhere to flavonoids, while compounds 13 , 15 and 16 belonged to alkynes. Flavonoids ( Albacha, Grayerb, & Jensen, 2003 ; Lai et al, 2007 ) possessed anti-inflammatory, analgesic and antioxidant, and the diverse biological activities including antibacterial, anti allergic, anti-inflammatory, analgesic, anti-tumor and inhibition of superoxide were reported for phenylpropanoids ( Wang et al, 2021 , Zhao et al, 2005 ) and alkynes (Nakamura et al, 1998; Wei, Li, Liu, & Liang, 2009 ), which are suitable as indicators of quality for A. ordosica grown in different ecological environments, are widely used in Mongolian traditional medicine for treatment of diverse diseases, especially for arthritis and rheumatoid. The content of these compounds in all samples varied from (1.099 ± 0.015) to (1.623 ± 0.025) mg/g of 1 , (1.102 ± 0.011) to (1.568 ± 0.018) mg/g of 2 , (0.998 ± 0.013) to (1.263 ± 0.018) mg/g of 5 , (1.201 ± 0.018) to (1.457 ± 0.023) of 8 , (0.693 ± 0.013) to (0.881 ± 0.015) mg/g of 9 , (1.165 ± 0.018) to (1.306 ± 0.022) mg/g of 12 , (0.836 ± 0.015) to (1.007 ± 0.018) mg/g of 13 , (1.150 ± 0.018) to (1.222 ± 0.023) mg/g of 15 , (1.768 ± 0.033) to (2.350 ± 0.041) mg/g of 16 .…”

Cu3P Nanoarrays Derived from 7,7,8,8-Tetracyanoquinodimethane for High-Rate Electrocatalytic Oxygen Reactions of Lithium-Oxygen Batteries

“…and even metal-free compounds [18][19][20][21][22][23][24][25][26][27]. Furthermore, numerous combinations of catalysts based on cobalt, iron, nickel, copper oxides/hydroxides, and carbon-based materials have been explored as prospective bifunctional oxygen catalysts [28][29][30][31][32][33].…”