Projections of the prevalence of hyperglycaemia in pregnancy in 2019 and beyond: Results from the International Diabetes Federation Diabetes Atlas, 9th edition

Abstract

This study aims to examine the projected HIP prevalence in 2030 and 2045 using multiple methods. Methods: The International Diabetes Federation Diabetes Atlas 2019 prevalence was projected to 2030 and 2045 by: (1) carrying forward the 2019 age-adjusted prevalence rates; (2) applying a linear regression of the past four editions of the IDF Diabetes Atlas; (3) applying a regression of the previous editions with the most consistent trend, followed by extrapolation from the 9th edition HIP estimate. Results: Respectively, for 2030 and 2045, Method 1 projected a declining HIP rate with prevalences of 14.0% and 13.3%, Method 2 projected an increasing HIP prevalence at 16.5% and 18.3%, Method 3 predicted stabilisation of the rate from 16.0% to 15.8%. Conclusion: Assuming other factors remain unchanged, our best estimation of age-adjusted HIP will show stabilisation between 2019 and 2045 of 15.8% to 16.0%. However, this estimate is confounded by the heterogeneity of studies and the influence of different gestational diabetes mellitus diagnostic criteria. To provide accurate future comparisons we recommend standardising the diagnostic criteria to the International Association of Diabetes in Pregnancy Study Groups.

Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition

“…The estimates are based on the most recent highquality epidemiological data available. Estimates and projections for hyperglycaemia in pregnancy (HIP), including GDM are provided in a separate paper (Simmons et al, in press) [9]. The complex and important aspects of diabetes in the elderly population are the subject of a separate paper in preparation.…”

Inhibitory evaluation ofCurculigo latifoliaon α-glucosidase, DPP (IV) andin vitrostudies in antidiabetic with molecular docking relevance to type 2 diabetes mellitus

“…However, if this does not recover or reduced, this figure is expected to rise around 700 million by 2045 and based on records, almost 49.7% was undiagnosed and living without knowing they had this disease 2 . Globally, based on the records, 374 million of people is at risk due to the developing in type 2 diabetes mellitus (T2DM), hence these evolution is increasing awareness of people about T2DM 3 . Type 2 diabetes mellitus or shortly known as T2DM is a type of diabetes disease that has features of insulin resistance from the decrease in the peripheral glucose uptake in most of the targeted tissue.…”

Serum 25-hydroxyvitamin D levels in relation to lipids and clinical outcomes in pregnant women with gestational diabetes mellitus: an observational cohort study

“…Open access pregnant women have a severe deficiency of vitamin D. 1 Vitamin D deficiency is also common among pregnant women in China. The TG/high-density lipoprotein cholesterol (HDL-c) ratio may be a good marker to identify insulin-resistant Chinese individuals 4 and is positively associated with diabetes risk.…”

“…The total prevalence of GDM in China is 14.8%. 1 Because of the adaptations to pregnancy, pregnant women will have some physiological changes in lipid metabolism. 2 Vitamin D is a necessary fat-soluble vitamin for the human body; it is involved not only in regulating calcium and phosphorus metabolism, but also in improving insulin resistance, regulating insulin secretion and blood lipid metabolism.…”