Prolactin in response to acute psychosocial stress in healthy men and women

Lennartsson, Anna-Karin; Jonsdottir, Ingibjörg H.

doi:10.1016/j.psyneuen.2011.04.007

Cited by 127 publications

(72 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Also, the levels were unchanged or decreased in few of the participants. Earlier we reported that the magnitude of response of the anterior pituitary hormone prolactin is closely related to the magnitude of response of ACTH, cortisol and heart rate, thus the general physiological stress activation (Lennartsson and Jonsdottir, 2011). In this study of sex hormone responses during stress, we observed similar patterns, but not as pronounced.…”

Section: Inter-individual Variation Of Sex Hormone Changes Among the supporting

confidence: 73%

Sex steroid levels temporarily increase in response to acute psychosocial stress in healthy men and women

Lennartsson

Kushnir

Bergquist

et al. 2012

International Journal of Psychophysiology

Self Cite

View full text Add to dashboard Cite

Section: Inter-individual Variation Of Sex Hormone Changes Among the supporting

confidence: 73%

Sex steroid levels temporarily increase in response to acute psychosocial stress in healthy men and women

Lennartsson

Kushnir

Bergquist

et al. 2012

International Journal of Psychophysiology

Self Cite

View full text Add to dashboard Cite

“…The magnitude of the prolactin response seems to be related to the magnitude of the response of the HPA axis and, to some extent, cardiovascular responses to stress. 102 The role of fluctuating levels of prolactin in spermatogenesis needs further clinical study.…”

Section: Prolactinmentioning

confidence: 99%

Effects of psychological stress on male fertility

2015

View full text Add to dashboard Cite

Psychological stress can be defined as any uncomfortable 'emotional experience' accompanied by predictable biochemical, physiological and behavioural changes or responses. Many clinical studies looking at the effects of psychological stress on male fertility have shown that stress is associated with reduced paternity and abnormal semen parameters. Enough scientific evidence exists to suggest that psychological stress could severely affect spermatogenesis, mainly as a result of varying testosterone secretion. The hypothalamic-pituitary-adrenal axis has a direct inhibitory action on the hypothalamic-pituitary-gonadal (HPG) axis and Leydig cells in the testes. The newly discovered hormone, gonadotropin-inhibitory hormone (GnIH), also has an inhibitory effect on the HPG axis. Inhibition of the HPG axis results in a fall in testosterone levels, which causes changes in Sertoli cells and the blood-testis barrier, leading to the arrest of spermatogenesis. Germ cells also become vulnerable to gonadotoxins and oxidation. However, the extent and severity of the effects of psychological stress on human testes is difficult to study and data mostly come from animal models. Despite this limitation, stress as a causative factor in male infertility cannot be ignored and patients should be made aware of its effects on testicular function and fertility and helped to manage them.

show abstract

“…Prolactin secretion is also affected by temperament, but most studies have investigated the prolactin response to stimuli, rather than in the absence of stressors [10][11][12][13]. The magnitude of the prolactin response to stimuli is correlated with temperament in humans and cattle [10][11][12][13], and, in humans, prolactin responses to stimuli are positively correlated with the cortisol response [13][14][15]. However, to our knowledge, the impact of temperament on the diurnal pattern of prolactin secretion in the absence of stressors, in relationship with the activity of the hypothalamic-pituitary-adrenal (HPA) axis, has not been investigated.…”

Section: Introductionmentioning

confidence: 99%