Proliferative Lesions of the Endometrium of 50 Four-Toed Hedgehogs (Atelerix albiventris)

Chambers, James K.; Shiga, Takanori; Takimoto, Haruka; Dohata, Atsushi; Miwa, Yoshiyuki; Nakayama, Hiroyuki; Uchida, Kazuyuki

doi:10.1177/0300985818758467

Cited by 18 publications

(12 citation statements)

References 56 publications

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“…The presence of ascites has been reported in hedgehogs with proliferative uterine lesions [3] and granulosa cell tumors [7]. In this study, ascites was identified in 50% patients.…”

Section: The Medical Records Of Eight Hedgehogs Admitted To Miwa Exotsupporting

confidence: 54%

Granulosa cell tumor in 8 African pygmy hedgehogs (Atelerix albiventris)

Wu¹,

Nakata²,

Chambers

et al. 2021

J. Vet. Med. Sci.

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A retrospective study involving eight African pygmy hedgehogs histopathologically diagnosed with granulosa cell tumors was conducted. The age at onset was 2.2-4.5 years, with a median age of 3.6 years. The most common clinical signs were hematuria and abdominal distension, which were observed in >50% cases. Exploratory laparotomy was performed in all cases, and ovariohysterectomy or excision of the abdominal mass was performed. Patients with only hematuria survived for >250 days after surgery, whereas those with initial ascites showed recurrence of ascites or tumor growth and survived for approximately 130 days after surgery. Intraperitoneal injection of carboplatin was performed in three recurrent cases. In one of these three cases, the tumor mass disappeared. Hence, carboplatin can be considered a potential antineoplastic drug for the treatment of granulosa cell tumors.

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“…The presence of ascites has been reported in hedgehogs with proliferative uterine lesions [3] and granulosa cell tumors [7]. In this study, ascites was identified in 50% patients.…”

Section: The Medical Records Of Eight Hedgehogs Admitted To Miwa Exotsupporting

confidence: 54%

Granulosa cell tumor in 8 African pygmy hedgehogs (Atelerix albiventris)

Wu¹,

Nakata²,

Chambers

et al. 2021

J. Vet. Med. Sci.

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“… ). These uterine polyps were classified histologically into 3 categories, based on the World Health Organization (WHO) classification for humans [ 2 , 13 ], and included one non-neoplastic and 2 neoplastic lesions.…”

Section: Resultsmentioning

confidence: 99%

A retrospective study of disease incidence in African pygmy hedgehogs (Atelerix albiventris)

Okada¹,

Kondo

Sumi³

et al. 2018

The Journal of Veterinary Medical Science

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The African pygmy hedgehog (Atelerix albiventris) is becoming a popular pet in Japan. The aim of this study was to determine the incidence of various diseases in African pygmy hedgehogs. We histologically investigated 105 samples from 100 privately-owned pet African pygmy hedgehogs that were submitted to two laboratories (North Lab and Patho Labo) between 2012 and 2017. Tissues submitted for this study were taken from female reproductive organs (33 cases; 31.43%), skin (20 cases; 19.05%), and the oral mucosa (19 cases; 18.1%). The most common histological diagnoses included endometrial stromal nodules identified as benign uterine neoplasia (14 cases; 13.33%); endometrial polyps identified as non-neoplastic polyps (7 cases; 6.67%), gingival hyperplasia and chronic suppurative inflammation in the oral mucosa (11 cases; 10.48%), fibrosarcomas in the skin (8 cases; 7.62%), and mammary tumors (8 cases; 7.62%). In this study, lymphoma and oral squamous cell carcinoma were less common than in the previous reports. The present study revealed the disease prevalence in captive African pygmy hedghogs that were histopathologically examined.

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“…A wide variety of neoplasms are commonly present in captive hedgehogs, especially in the APH (Raymond and Gamer 2001;Gadrhouse and Eshar 2015;Tsai et al 2016;Chambers et al 2018). The average lifespan of the APH is 3-5 years and the average age for the appearance of neoplasms is 3.5 years (Heatley 2009;Matute et al 2014).…”

Section: Discussionmentioning

confidence: 99%

Endometrial polyp with chronic endometritis in an African pygmy hedgehog (Atalerix albiventris) – a case report

et al. 2019

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An African pygmy hedgehog (Atalerix albiventris) (APH) was admitted to the clinic with a history of vaginal bleeding. Examination showed poor clinical status of the patient based on haemogram values. The ultrasound showed an enlarged uterus filled with an anechoic content without the presence of free abdominal fluid. Ovariohysterectomy was performed under general inhalation anaesthesia. Histopathology examination was performed on tissue samples of the uterus with the final diagnosis of an endometrial polyp with endometrial cystic hyperplasia and chronic endometritis. In regard to the diagnostic findings, therapeutic option and postoperative care performed in this case, it is important to emphasize the fact that an early diagnosis of a reproductive disease contributes to proper treatment and a positive outcome. The endometrial polyp with cystic endometrial hyperplasia and chronic endometritis should be added to the list of differential diagnoses in cases where neoplasia of the reproductive system is suspected in an APH.

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Proliferative Lesions of the Endometrium of 50 Four-Toed Hedgehogs (Atelerix albiventris)

Cited by 18 publications

References 56 publications

Granulosa cell tumor in 8 African pygmy hedgehogs (<i>Atelerix albiventris</i>)

Granulosa cell tumor in 8 African pygmy hedgehogs (<i>Atelerix albiventris</i>)

A retrospective study of disease incidence in African pygmy hedgehogs (<i>Atelerix albiventris</i>)

Endometrial polyp with chronic endometritis in an African pygmy hedgehog (Atalerix albiventris) – a case report

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