Prolonged anesthesia with desflurane and fentanyl in dogs during conventional and laparoscopic surgery

Abstract

Results suggest that induction of anesthesia with propofol and maintenance with desflurane and fentanyl is safe in dogs undergoing abdominal surgery.

Köpeklerde kısa süreli uygulanan propofolün pankreatitis oluşumuna etkisi

“…(19) yaptığı bir araştırmada propofolü köpeklere dört farklı dozda uygulamış ve yüksek dozların apneye daha çok neden olduğunu kaydetmişlerdir. İndüksiyon amacı ile uygulanan propofolün yavaş uygulandığı takdirde apneye neden olmadığını bildiren başka çalışmalar da mevcuttur (1,6,11,14,17,18,22). Bu çalışmada hiçbir hayvanda apne görülmemesi propofolün yavaş uygulanmasına ve entübasyon için yeterli derinlikte anestezi sağ-landıktan sonra uygulamanın sonlandırılmasına bağlan-mıştır.…”

Organisation der postoperativen Schmerztherapie Deutschlands im europäischen Vergleich - Ergebnisse einer europaweiten Umfrage (PATHOS)

“…Ihre Ergebnisse zeigten regelmäßig, dass postoperativer akuter Schmerz unabhängig von der geographischen Lage oder der akademischen Ausrichtung der betreuenden Klinik nicht zufriedenstellend behandelt wird. In den vergangenen Jahrzehnten wurden daher zahlreiche nationale und internationale Initiativen zur Verbesserung der Akutschmerztherapie gestartet, Leitlinien verfasst [1,2,3,4,12,14] und wissenschaftliche Gesellschaften und Arbeitsgemeinschaften gegründet. Obwohl sich behandelnde Ärzte der besonderen Bedeutung einer effektiven postoperativen Schmerztherapie bewusst sind und heute auch weitestgehend unumstritten ist, dass eine optimierte Schmerztherapie im Rahmen definierter klinischer Behandlungspfade die Ergebnisse chirurgischer Eingriffe deutlich verbessern kann [8,10,11,22], haben wiederholte Umfragen in Deutschland [15,16,23] und anderen Nationen [18,20,21,27] keine wesentlichen Verbesserungen demonstrieren können.…”

Comparison of cardiopulmonary responses during sedation with epidural and local anesthesia for laparoscopic-assisted jejunostomy feeding tube placement with cardiopulmonary responses during general anesthesia for laparoscopic-assisted or open surgical jejunostomy feeding tube placement in healthy dogs

“…[5][6][7][8] Differences in anesthetic protocol, duration of the procedure, patient positioning, insufflation pressures, and preexisting health status have caused disparity in reported hemodynamic abnormalities during laparoscopic procedures. Cardiopulmonary effects of laparoscopy performed under general anesthesia are described for dogs, [8][9][10][11][12] horses, 13 and humans. 14,15 These studies reported increased MAP, [8][9][10]13,14 SVR, [13][14][15] and VE 9 and decreased CO, 11,13,15 arterial pH, 9,12,13,16 and Pao 2 .…”

“…Cardiopulmonary effects of laparoscopy performed under general anesthesia are described for dogs, [8][9][10][11][12] horses, 13 and humans. 14,15 These studies reported increased MAP, [8][9][10]13,14 SVR, [13][14][15] and VE 9 and decreased CO, 11,13,15 arterial pH, 9,12,13,16 and Pao 2 . 9,13,16 Heart rate was increased in some studies 9,14 but remained unchanged in others.…”

“…11 Changes in hemodynamic parameters are generally proportional to the rate and degree of abdominal insufflation and are decreased with IAPs > 20 mm Hg. 16 In fact, results of several studies indicate that creation of capnoperitoneum with insufflation pressures of < 15 mm Hg did not interfere significantly with pulmonary gas exchange and did not cause significant hypercarbia in healthy dogs [8][9][10] or human patients. 12,14,23 In humans, laparoscopic procedures are frequently performed with combinations of sedation, local infiltration, and epidural anesthesia to minimize the depressant effects of general anesthesia, especially with critically ill or compromised patients, [24][25][26][27][28] and are associated with better postoperative recovery, reduced analgesic requirements, and shorter hospitalizations.…”