Prolonged Symptoms after COVID-19 in Japan: A Nationwide Survey of the Symptoms and Their Impact on Patients’ Quality of Life

Honda, Hiroaki; Takamatsu, Akane; Miwa, Toshiki; Tabuchi, Takahiro; Taniguchi, Kiyosu; Shibuya, Kenji; Tokuda, Yasuharu

doi:10.1016/j.amjmed.2023.04.040

Cited by 6 publications

(2 citation statements)

References 22 publications

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“…Regarding multimorbidity, a study [8] conducted with older adults in Canada showed that having two or more morbidities had a 1.90 (95% CI Hypotheses point to the mechanism of long COVID through long-term tissue damage to organs such as the lungs, brain, and heart, and a pathological in ammation due to viral persistence, immune dysregulation, and autoimmunity, among others, which may likely contribute to the hyperactivation of monocyte-derived macrophages in the acute and post-acute phases of the disease [7,[37][38][39][40][41][42][43][44].…”

Section: Discussionmentioning

confidence: 99%

MULTIMORBIDITY, MORBIDITIES, AND LONG COVID – findings of the Sulcovid longitudinal study

Ventura,

Vieira,

Rocha

et al. 2024

Preprint

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Background The aim of this study was to evaluate the association between long COVID, morbidities, and multimorbidity in adults and older adults six to nine months after infection with the SARS-CoV-2 virus in Southern Brazil. Methods Baseline data were obtained from the longitudinal study, Sulcovid, conducted on individuals diagnosed with COVID-19 through RT-PCR testing from December 2020 to March 2021, who were symptomatic and living in a city in southern Brazil. Long COVID was assessed based on the affirmative response to at least one of the 18 symptoms investigated and categorized as musculoskeletal, neurological, respiratory, sensory, or digestive. Morbidities were assessed based on the presence of at least one of nine self-reported diseases. Data were analyzed using the Stata 15.0 statistical package. Crude and adjusted analyses were performed using Poisson regression to assess the relationships between morbidity, multimorbidity, and long COVID. Results In total, 2,919 people were interviewed. The most prevalent morbidities were anxiety (26.3%), hypertension (25.3%), and depression (19.4%). In addition, 17.8% reported two previous morbidities and 22.6% had three or more comorbidities. Individuals with depression (PR = 1.17 95% CI 1.05–1.30), anxiety (PR = 1.33 95% CI 1.21–1.47), two or more morbidities (PR = 1.22 95% CI 1.07–1.39), and three or more morbidities (PR = 1.40; 95% CI 1.24–1.57) were more likely to have long COVID. A linear trend was observed, where individuals with two and three or more morbidities were 1.22 (95% CI 1.07–1.39) and 1.40 (95% CI 1.24–1.57) times more likely to develop long COVID than those with no or one morbidity. Conclusions The findings of this study reinforce that individuals with morbidities and multimorbidities prior to infection had greater vulnerability to long COVID.

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Section: Discussionmentioning

confidence: 99%

MULTIMORBIDITY, MORBIDITIES, AND LONG COVID – findings of the Sulcovid longitudinal study

Ventura,

Vieira,

Rocha

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…The categories used in this study to classify essential workers were identical to those used by the Advisory Committee on Immunization Practices (ACIP). 12 The exclusion criteria were the same as those in a previous study and are reproduced below for convenience: 13 (1) failure to provide a correct response to an attention-check question; (2) a history of using all 10 categories of drug listed (nine categories in the JACSIS2022); (3) the presence of all 20 health conditions listed; (4) family members >15.…”

Section: Data Collectionmentioning

confidence: 99%

Association of Individual Behaviors With Infection Prevention Measures and COVID-19 Development: A Japanese Cross-Sectional Study

Honda,

Takamatsu,

Miwa

et al. 2024

Asia Pac J Public Health

Self Cite

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During the COVID-19 pandemic, people often modified their behaviors and performed individual infection control practices despite the uncertain effectiveness of these in preventing COVID-19. A cross-sectional study using a nationwide internet survey (Japan COVID-19 Society Internet Survey) was conducted from September 2022 through October 2022. The questionnaire consisted of individual-level social distancing behaviors and infection prevention measures, and COVID-19 vaccination status. A multivariate logistic regression was performed to determine factors associated with the diagnosis of COVID-19 in the last 2 months of the survey date. In total, 19,296 respondents were selected for the primary analysis. Of 19,296 respondents, those with COVID-19 diagnosed in the last 2 months were 1,909 (9.9%). Factors independently associated with a recent history of COVID-19 were meeting colleagues in person ≧ 1 per week (adjusted odds ratio [aOR] 1.72, 95% confidence interval [CI] 1.36-2.19, P < .001). The response of “never or rarely” to the question of taking out (ie, dining in) foods was marginally associated with a recent history of COVID-19 (aOR 1.27, 95% CI 0.99-1.63, P = .06). Most individual, infection prevention practices and behavioral modifications during the omicron variant phase of the pandemic did not substantially impact COVID-19 prevention in the community.

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Reduced HDL-cholesterol in long COVID-19: A key metabolic risk factor tied to disease severity

Al-Zadjali,

Al-Lawati,

Al Riyami

et al. 2024

Clinics

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Prolonged Symptoms after COVID-19 in Japan: A Nationwide Survey of the Symptoms and Their Impact on Patients’ Quality of Life

Cited by 6 publications

References 22 publications

MULTIMORBIDITY, MORBIDITIES, AND LONG COVID – findings of the Sulcovid longitudinal study

MULTIMORBIDITY, MORBIDITIES, AND LONG COVID – findings of the Sulcovid longitudinal study

Association of Individual Behaviors With Infection Prevention Measures and COVID-19 Development: A Japanese Cross-Sectional Study

Reduced HDL-cholesterol in long COVID-19: A key metabolic risk factor tied to disease severity

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