Promises and Challenges of Microalgal Antioxidant Production

Sansone, Clementina; Brunet, Christophe

doi:10.3390/antiox8070199

Cited by 92 publications

(68 citation statements)

References 75 publications

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“…Indeed, marine organisms represent a rich source of antioxidants, in terms of quantity and/or diversity. Vitamins B 12 , C, D, E, peptides, amino acids, chitooligosaccharide derivatives, carotenoids, sulphated polysaccharides, sterols, phlorotannins, phenolic compounds and flavones are examples of marine antioxidant richness [16].…”

Section: Introductionmentioning

confidence: 99%

Marine Algal Antioxidants as Potential Vectors for Controlling Viral Diseases

et al. 2020

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As the COVID-19 epidemic expands in the world, and with the previous SARS epidemic, avian flu, Ebola and AIDS serving as a warning, biomedical and biotechnological research has the task to find solutions to counteract viral entry and pathogenesis. A novel approach can come from marine chemodiversity, recognized as a relevant source for developing a future natural "antiviral pharmacy". Activities of antioxidants against viruses can be exploited to cope with human viral infection, from single individual infections to protection of populations. There is a potentially rich and fruitful reservoir of such compounds thanks to the plethora of bioactive molecules and families present in marine microorganisms. The aim of this communication is to present the state-of-play of what is known on the antiviral activities recognized in (micro)algae, highlighting the different molecules from various algae and their mechanisms of actions, when known. Given the ability of various algal molecules-mainly sulfated polysaccharides-to inhibit viral infection at Stage I (adsorption and invasion of cells), we envisage a need to further investigate the antiviral ability of algae, and their mechanisms of action. Given the advantages of microalgal production compared to other organisms, the opportunity might become reality in a short period of time.

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Section: Introductionmentioning

confidence: 99%

Marine Algal Antioxidants as Potential Vectors for Controlling Viral Diseases

et al. 2020

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“…Antioxidant molecules have gained great interest lately [41], and microalgae stand for a nearly intact resource of natural antioxidants because of their vast biodiversity, which is much more diverse than higher plants [73]. On the other hand, not all groups of microalgae can be applied as natural sources of antioxidants because of their broadly diverse content of products and non-favorable growth rate, as well as some other factors [55].…”

Section: Marine Bacteriamentioning

confidence: 99%

Marine Bacteria versus Microalgae: Who Is the Best for Biotechnological Production of Bioactive Compounds with Antioxidant Properties and Other Biological Applications?

Hamidi

Kozani

et al. 2019

Marine Drugs

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Natural bioactive compounds with antioxidant activity play remarkable roles in the prevention of reactive oxygen species (ROS) formation. ROS, which are formed by different pathways, have various pathological influences such as DNA damage, carcinogenesis, and cellular degeneration. Incremental demands have prompted the search for newer and alternative resources of natural bioactive compounds with antioxidant properties. The marine environment encompasses almost three-quarters of our planet and is home to many eukaryotic and prokaryotic microorganisms. Because of extreme physical and chemical conditions, the marine environment is a rich source of chemical and biological diversity, and marine microorganisms have high potential as a source of commercially interesting compounds with various pharmaceutical, nutraceutical, and cosmeceutical applications. Bacteria and microalgae are the most important producers of valuable molecules including antioxidant enzymes (such as superoxide dismutase and catalase) and antioxidant substances (such as carotenoids, exopolysaccharides, and bioactive peptides) with various valuable biological properties and applications. Here, we review the current knowledge of these bioactive compounds while highlighting their antioxidant properties, production yield, health-related benefits, and potential applications in various biological and industrial fields.

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“…Nannochloropsis oculata has been widely developed, not only for the production of therapeutic agents in the pharmaceutical industry [6,7], but also for the production of nutrients [8], food [9], and biofuel. N. oculata is also regarded as attractive because it can be grown in brackish water and seawater.…”

Section: Introductionmentioning

confidence: 99%

Magnetophoretic Harvesting of Nannochloropsis oculata Using Iron Oxide Immobilized Beads

Chu

Wan

Chen

et al. 2020

Water

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In this work, the harvesting of Nannochloropsis oculata microalgae through the use of nanosized Fe3O4 immobilized in polyvinyl alcohol (PVA)/sodium alginate (SA) as a flocculant (Fe3O4/PS) is investigated. Using the Fe3O4/PS immobilized beads could reduce the amount of soluble ferrous ions (Fe2+) released from naked Fe3O4 in acid treatment, leading to easy recovery. The characterization was performed under different dosages and pH values of Fe3O4/PS. The results show that the Fe3O4/PS, when applied to the algae culture (500 mg dry cell weight/L), achieves a 96% harvesting efficiency under conditions of a pH of 4 with 200 mT magnetic field intensity. Fe3O4/PS can be directly reused without adjusting the pH value. The recycled Fe3O4/PS shows stability in terms of its surface properties, maintaining more than 80% harvesting efficiency after five recycles. Magnetophoretic harvesting, using immobilized magnetic iron oxide as a particle-based flocculant, is a potential method to reduce challenges related to the cost-effective microalgae-harvesting method.

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Promises and Challenges of Microalgal Antioxidant Production

Cited by 92 publications

References 75 publications

Marine Algal Antioxidants as Potential Vectors for Controlling Viral Diseases

Marine Algal Antioxidants as Potential Vectors for Controlling Viral Diseases

Marine Bacteria versus Microalgae: Who Is the Best for Biotechnological Production of Bioactive Compounds with Antioxidant Properties and Other Biological Applications?

Magnetophoretic Harvesting of Nannochloropsis oculata Using Iron Oxide Immobilized Beads

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