Understanding the dynamics of vegetative greenness and how it interacts with various hydroclimatic factors is crucial for comprehending the implications of global climate change. The present study utilized the MODIS-derived normalized difference vegetation index (NDVI) to understand the vegetation patterns over 21 years (2001–2021) in Rajasthan, India. The rainfall, land surface temperature (LST), and evapotranspiration (ET) were also analyzed. The changes, at a 30 m pixel resolution, were evaluated using Mann–Kendall’s trend test. The results reveal that the NDVI, ET, and rainfall had increasing trends, whereas the LST had a decreasing trend in Rajasthan. The NDVI increased for 96.5% of the total pixels, while it decreased for 3.4% of the pixels, of theh indicates vegetation improvement rather than degradation. The findings of this study provide direct proof of a significant reduction in degraded lands throughout Rajasthan, particularly in the vicinity of the Indira Gandhi Canal command area. Concurrently, there has been a noticeable expansion in the cultivated land area. The trend of vegetation decline, particularly in the metro cities, has occurred as a result of urbanization and industrialization. In contrast to the LST, which has a decreasing gradient from the western to eastern portions, the spatial variability in the NDVI, ET, and rainfall have decreasing gradients from the southern and eastern to western regions. The results of correlations between the vegetative indices and hydroclimatic variables indicate that the NDVI has a strong positive correlation with ET (r2 = 0.86), and a negative correlation with LST (r2 = −0.55). This research provides scientific insights into vegetation change across Rajasthan, and may help the state to monitor vegetation changes, conserve ecosystems, and implement sustainable ecosystem management.