Propacetamol and diclofenac alone and in combination for analgesia after elective tonsillectomy

Abstract

Combined treatment with propacetamol and diclofenac with the dosages used provided clinically only a minor advantage over monotherapy with propacetamol or diclofenac with respect to postoperative analgesia or the incidence of side-effects in adult tonsillectomy patients.

Pre‐operative analgesia with rectal diclofenac and/or paracetamol in children undergoing inguinal hernia repair

“…Rømsing and his group in their systematic review reported that concurrent use of paracetamol and an NSAID was superior to paracetamol but not to NSAID [21]. In contrast, Hiller and his colleagues [22] reported that combined therapy with propacetamol and diclofenac offered no clinical advantage over monotherapy as regards postoperative analgesia in adult elective tonsillectomy patients. The difference between studies could be attributed to the study design, type of the procedure and selected population.…”

A cross-sectional study to assess the rationality of fixed dose combinations prescribed in geriatric patients in a tertiary care hospital

“…1,11 Combination of two nonsteroidal anti-inflammatory drugs (diclofenac, naproxen, etodolac) with paracetamol was commonly used in our study, but when both are added the increase in efficacy is not much. 12 FDCs of diclofenac+serratopeptidase do not offer any particular advantage over the individual drugs despite the claim that serratopeptidase promotes more rapid resolution of inflammation. 13 Dicyclomine and paracetamol combination is highly irrational as paracetamol promotes sweating and thereby helps in heat dissipation.…”

Assesment of The Effect of Multimodal Preemptive Analgesia in Children

“…19 In this study we used analgesic at optimum dose and regular basis in both control group and study group.…”