European Journal of Anaesthesiology

1997

DOI: 10.1097/00003643-199705001-00017

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Propacetamol vs Diclofenac and Placebo for Postoperative Pain Control After Total Hip Arthroplasty

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Michele L. McCarroll

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et al.

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Single dose oral diclofenac for acute postoperative pain in adults

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et al. 2004

Cochrane Database of Systematic Reviews

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Oral diclofenac is an effective single-dose treatment for moderate to severe postoperative pain. There was no significant difference between diclofenac and placebo in the incidence of adverse effects, or between diclofenac sodium and potassium, different pain models, smaller and larger trials and trials of higher and lower quality.

Single dose oral diclofenac for acute postoperative pain in adults

¹

,

et al. 2004

Cochrane Database of Systematic Reviews

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Oral diclofenac is an effective single-dose treatment for moderate to severe postoperative pain. There was no significant difference between diclofenac and placebo in the incidence of adverse effects, or between diclofenac sodium and potassium, different pain models, smaller and larger trials and trials of higher and lower quality.

Single-dose intravenous diclofenac for acute postoperative pain in adults

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2018

Cochrane Database of Systematic Reviews

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The amount and quality of evidence for the use of intravenous diclofenac as a treatment for postoperative pain is low. The available evidence indicates that postoperative intravenous diclofenac administration offers good pain relief for the majority of patients, but further research may impact this estimate. Adverse events appear to occur at a similar rate to other NSAIDs. Insufficient information is available to assess whether intravenous diclofenac has a different rate of bleeding, renal dysfunction, or cardiovascular events versus other NSAIDs. There was insufficient information to evaluate the efficacy and safety of newer versus traditional formulations of intravenous diclofenac. There was a lack of studies in major and cardiovascular surgeries and in elderly populations, which may be at increased risk for adverse events.

Le propacétamol: des données fondamentales à l'utilisation clinique

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et al. 1999

Annales Françaises d'Anesthésie et de Réanimation

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