Properties and use of a honey dressing and gel in wound management

Henry, Nader; Jeffery, Steven; Radotra, Ishan

doi:10.12968/bjon.2019.28.6.s30

Cited by 13 publications

(8 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some advantages of using MGH are that it is safe, easy to apply, and cost-effective for the treatment of severe wounds, burns, ulcers, oral mucositis in young pediatric patients, and in those suffering from cancer [ 56 , 57 ]. Honey’s anti-inflammatory effect and ability to treat local infections, promote autolytic debridement, disinfect wounds, and promote granulation tissue, which have been confirmed in previous literature [ 58 ]. A study evaluated the efficacy of honey in the treatment of wounds of lower leg and diabetic ulcers.…”

Section: Mgh and Its Wound Healing Effectssupporting

confidence: 62%

Honey in wound healing: An updated review

Tashkandi

2021

Open Life Sciences

View full text Add to dashboard Cite

Wound healing is a complex process with many interdependent pathophysiological and immunological mediators to restore the cellular integrity of damaged tissue. Cutaneous wound healing is the repair response to a multitude of pathologies induced by trauma, surgery, and burn leading to the restoration and functionality of the compromised cells. Many different methods have been employed to treat acute and chronic wounds, such as antimicrobial therapy, as most wounds are susceptible to infection from microbes and are difficult to treat. However, many antimicrobial agents have become ineffective in wound treatment due to the emergence of multiple drug-resistant bacteria, and failures in current wound treatment methods have been widely reported. For this reason, alternative therapies have been sought, one of which is the use of honey as a wound treatment agent. The use of honey has recently gained clinical popularity for possible use in wound treatment and regenerative medicine. With this high demand, a better delivery and application procedure is required, as well as research aiming at its bioactivity. Honey is a safe natural substance, effective in the inhibition of bacterial growth and the treatment of a broad range of wound types, including burns, scratches, diabetic boils (Skin abscesses associated with diabetic), malignancies, leprosy, fistulas, leg ulcers, traumatic boils, cervical and varicose ulcers, amputation, burst abdominal wounds, septic and surgical wounds, cracked nipples, and wounds in the abdominal wall. Honey comprises a wide variety of active compounds, including flavonoids, phenolic acid, organic acids, enzymes, and vitamins, that may act to improve the wound healing process. Tissue-engineered scaffolds have recently attracted a great deal of attention, and various scaffold fabrication techniques are being researched. Some incorporate honey to improve their delivery during wound treatment. Hence, the aim of this review is to summarize recent studies on the wound healing properties of honey.

show abstract

Section: Mgh and Its Wound Healing Effectssupporting

confidence: 62%

Honey in wound healing: An updated review

Tashkandi

2021

Open Life Sciences

View full text Add to dashboard Cite

show abstract

“…Natural compounds such as propolis, honey, quercetin, and silk fibroin can be associated with films or nanofibers dressings to improve their biocompatibility, antibacterial potential, remove the excess of exudate, and maintain wound moisture. In addition, in vitro and in vivo experiments confirm the influence of these biological dressings in reepithelialization and collagen deposition [81][82][83][84]. Antibiotic drugs and composites can be associated with biological dressings to improve their healing activities.…”

Section: Dressingsmentioning

confidence: 75%

Cutaneous Wound Healing: An Update from Physiopathology to Current Therapies

Gushiken

Beserra

Bastos

et al. 2021

Life

139

View full text Add to dashboard Cite

The skin is the biggest organ of human body which acts as a protective barrier against deleterious agents. When this barrier is damaged, the organism promotes the healing process with several molecular and cellular mechanisms, in order to restore the physiological structure of the skin. The physiological control of wound healing depends on the correct balance among its different mechanisms. Any disruption in the balance of these mechanisms can lead to problems and delay in wound healing. The impairment of wound healing is linked to underlying factors as well as aging, nutrition, hypoxia, stress, infections, drugs, genetics, and chronic diseases. Over the years, numerous studies have been conducted to discover the correct approach and best therapies for wound healing, including surgical procedures and non-surgical treatments such as topical formulations, dressings, or skin substitutes. Thus, this general approach is necessary to facilitate the direction of further studies. This work provides updated concepts of physiological mechanisms, the factors that can interfere, and updated treatments used in skin wound healing.

show abstract

“…Medical honey also promotes the self-soluble removal of residual substances from wounds. Honey includes nutrients that are structurally comparable to those found in human tissues, which can help wounds heal faster [ 60 ]. (3) Iodine-based dressings: Iodine-based dressing is a polymeric material containing iodine, whose main components are iodine and gelatin and other macromolecular substances.…”

Section: Diabetic Wounds and Diabetic Dressingsmentioning

confidence: 99%

Advances in the Preparation of Nanofiber Dressings by Electrospinning for Promoting Diabetic Wound Healing

Liu

Feng

et al. 2022

Biomolecules

View full text Add to dashboard Cite

Chronic diabetic wounds are one of the main complications of diabetes, manifested by persistent inflammation, decreased epithelialization motility, and impaired wound healing. This will not only lead to the repeated hospitalization of patients, but also bear expensive hospitalization costs. In severe cases, it can lead to amputation, sepsis or death. Electrospun nanofibers membranes have the characteristics of high porosity, high specific surface area, and easy functionalization of structure, so they can be used as a safe and effective platform in the treatment of diabetic wounds and have great application potential. This article briefly reviewed the pathogenesis of chronic diabetic wounds and the types of dressings commonly used, and then reviewed the development of electrospinning technology in recent years and the advantages of electrospun nanofibers in the treatment of diabetic wounds. Finally, the reports of different types of nanofiber dressings on diabetic wounds are summarized, and the method of using multi-drug combination therapy in diabetic wounds is emphasized, which provides new ideas for the effective treatment of diabetic wounds.

show abstract

Properties and use of a honey dressing and gel in wound management

Cited by 13 publications

References 16 publications

Honey in wound healing: An updated review

Honey in wound healing: An updated review

Cutaneous Wound Healing: An Update from Physiopathology to Current Therapies

Advances in the Preparation of Nanofiber Dressings by Electrospinning for Promoting Diabetic Wound Healing

Contact Info

Product

Resources

About