Propionic Acid

Lueck, Erich; Edwards, Grant F.

doi:10.1007/978-3-642-96570-8_23

Cited by 8 publications

(6 citation statements)

References 15 publications

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“…Propionic acid and its salts are widely used as anti-fungal agents in food [1], as additives in animal feeds [2,3], and as important thermoplastics in the plastic industry. Propionic acid and its salts can be obtained either by chemical reactions, which are chiefly conducted through the chemical synthesis of petroleum feedstocks or by fermentation using the bacteria of the genera Propionibacterium [4].…”

Section: Introductionmentioning

confidence: 99%

Microbial Production of Propionic Acid with Propionibacterium freudenreichii Using an Anion Exchanger-Based In Situ Product Recovery (ISPR) Process with Direct and Indirect Contact of Cells

Wang

2011

Appl Biochem Biotechnol

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The recovery of an inhibiting product from a bioreactor soon after its formation is an important issue in industrial bioprocess development. In the present study, the potential of the anion exchanger-based in situ product recovery (ISPR) technique for the biocatalytic production of propionic acid was discussed. The focus of the current work was the selection of a suitable configuration of metabolically active cells for application in propionic acid production. Accumulation of propionic acid in fermentation broth caused feedback inhibition of the growth and biotransformation activity of Propionibacterium freudenreichii CICC 10019. Relevant product inhibition kinetics was discussed, and the results showed that keeping the aqueous propionic acid concentration below 10.02 g L⁻¹ was an essential prerequisite for ISPR process. A batch study, in which three ISPR configuration mode designs were compared, was conducted. The comparison indicated that employing an external direct mode had significant advantages over other modes in terms of increased productivity and product yield, with a corresponding decrease in the number of downstream processing steps, as well as in substrate consumption. The fed-batch culture using an external direct mode for the continuous accumulation of propionic acid resulted in a cumulative propionic acid concentration of 62.5 g L⁻¹, with a corresponding product yield of 0.78 g propionic acid/g glucose.

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Section: Introductionmentioning

confidence: 99%

Microbial Production of Propionic Acid with Propionibacterium freudenreichii Using an Anion Exchanger-Based In Situ Product Recovery (ISPR) Process with Direct and Indirect Contact of Cells

Wang

2011

Appl Biochem Biotechnol

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“…As a preservative, propionic acid extends the shelf life of food products by inhibiting the growth of moulds and some bacteria [2][3][4] . Although preservatives derived from propionibacterium fermentations are available, most propionic acid used in the food industry have been produced by petrochemical synthesis 1 .…”

Section: Introductionmentioning

confidence: 99%

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Ahmad¹,

Othman²

2010

ScienceAsia

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ABSTRACT:In recent years, catalytic properties of gold have played a major role in the chemistry of environmentally safe substances. In this study, propionic acid was synthesized using electrochemical oxidation on a gold plate electrode in potassium hydroxide. Five hours of electrochemical reaction at a constant voltage was carried out using the chronocuolometry method. Propionaldehyde was oxidized electrochemically to propionic acid as verified by the characterization data from high performance liquid chromatography and Fourier transform infrared spectroscopy. The proposed mechanism of the reaction showed the importance of the OH -species in the synthesis reaction.

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“…The antimicrobial effect of propionic acid has been known since 19 13 (Kielsel 1913) and its application in food has been reviewed (Lueck and Jager 1997). More recently, antifungal effects of propionic acid have been investigated (Chourasia 1993;Ghosh and Haggblom 1985).…”

Section: Introductionmentioning

confidence: 99%

ANTIFUNGAL EFFECTS OF SORBIC ACID AND PROPIONIC ACID AT DIFFERENT pH AND NaCl CONDITIONS

Rohani

Griffiths

1999

Journal of Food Safety

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The effect of pH (7, 5.6, 3.5), NaCl concentration (3 to 20% w/v) and EDTA on the antifungal activity of sorbic acid and propionic acid (Ca salt) against Candida spp., Sporothrix sp., Fusarium sp., Penicillium spp., Paecilomyces sp. and Aspergillus spp. was investigated by the Spiral Gradient End Point Test. Sorbic acid was active against most yeasts and molds, and in the presence of EDTA, which enhanced the effect of sorbic acid, all the organisms tested were inhibited. Sorbic acid was most effective at low pH. The inhibitory effect of sorbic acid increased with increasing NaCl concentration for all test organisms. Propionic acid was not as active as sorbic acid, but when combined with EDTA the inhibition was improved for some of the molds tested. Increasing or decreasing the pH did not change the antifungal activity of propionic acid. Synergistic effects of NaCl occurred at concentrations higher than 10%, but when EDTA was added, the inhibition was seen even at the lower NaCl concentrations.

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Propionic Acid

Cited by 8 publications

References 15 publications

Microbial Production of Propionic Acid with Propionibacterium freudenreichii Using an Anion Exchanger-Based In Situ Product Recovery (ISPR) Process with Direct and Indirect Contact of Cells

Microbial Production of Propionic Acid with Propionibacterium freudenreichii Using an Anion Exchanger-Based In Situ Product Recovery (ISPR) Process with Direct and Indirect Contact of Cells

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ANTIFUNGAL EFFECTS OF SORBIC ACID AND PROPIONIC ACID AT DIFFERENT pH AND NaCl CONDITIONS

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